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Tag: Alzheimer’s

Strategies Needed to Improve Delivery of Alzheimer Disease-Modifying Therapies

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Models that enable primary care practitioners to diagnose and evaluate patients for treatment eligibility would have biggest impact on wait times

Monoclonal Antibodies Provide Small Benefits in Alzheimer Disease

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Harms include increased risks for amyloid-related imaging abnormalities (ARIA)-edema, ARIA-hemorrhage, and symptomatic ARIA-edema

Study IDs Proportion of Dementia Cases Attributable to Known Risk Factors

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PAF for nongenetic risk factors combined similar for men and women, but varies across racial, ethnic groups

Racial/Ethnic Minorities Underrepresented in Alzheimer Neuroimaging Research

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Sample diversity has improved recently, with proportion of Blacks increasing from 3.39 percent in 1994-2017 to 8.29 percent in 2018-2022

Light Therapy Aids Psychobehavioral Symptoms With Alzheimer Disease

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Significant benefits seen for sleep efficacy, depression, and agitation

Transcranial Direct Current Stimulation Beneficial in Alzheimer Disease

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Active tCDS improves cognitive functions in memory domain, including word recall, recall of test instructions, word recognition

Housing Instability Tied to Higher Risk for Dementia Diagnosis

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Findings show 40 percent higher risk among housing-insecure veterans

Gantenerumab Does Not Slow Clinical Decline in Early Alzheimer Disease

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Two trials show lower amyloid plaque burden with gantenerumab versus placebo at 116 weeks

Earlier Onset of A-Fib Linked to Risk of Developing All-Cause Dementia

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Younger age at a-fib onset linked to increased risks of all-cause and vascular dementia, Alzheimer disease

Stress, Depression Linked to MCI, Alzheimer Disease

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Chronic stress and depression are independent risk factors and have an additive effect when combined