Tag: Alzheimer’s
Short-Term PPIs Tied to Higher Hip Fracture Risk in Alzheimer’s
No association seen with long-term or cumulative proton pump inhibitor use in Alzheimer's patients
Molecular Markers May ID Alzheimer’s Before Clinical Onset
Amyloid-positive PSEN1 E280A mutation carriers have elevated levels of tau deposition before onset
Pimavanzserin Cuts Alzheimer’s Psychosis at Six Weeks
Significantly greater reduction in NPI-NH psychosis score at 6 weeks versus placebo, but not at 12 weeks
In Alzheimer’s, BACE1 Inhibition May Reverse Amyloid Deposition
Sequential, increased deletion of BACE1 in adult AD mouse model reversed amyloid deposition
Deep Brain Stimulation May Be Promising Alzheimer’s Treatment
DBS at ventral capsule/ventral striatum linked to less decline on Clinical Dementia Rating-Sum of Boxes
Solanezumab Doesn’t Affect Cognitive Decline in Alzheimer’s
No difference between the drug and placebo in change in ADAS cognitive subscale score at week 80
Idalopirdine May Not Improve Cognition in Mild Alzheimer’s
Findings from three randomized trials show no improvement in cognition vs. placebo over 24 weeks
Memory Scores Limited As Alzheimer’s Screening Tool
Scores are an early marker of amyloid positivity, but limited in value for those without dementia
Magnesium Boosts Environmental Enrichment in Alzheimer’s
Combination of EE, magnesium-L-threonate more effective than either treatment alone in mouse model
Retinal Sensitivity Linked to Cognitive Status in T2DM
Retinal sensitivity assessed by microperimetry is correlated with neurodegeneration parameters
