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Tag: Alzheimer’s

U.S. Sets Up $300 Million Database for Alzheimer Disease Research

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In creating the database, the goal is to provide something that can 'improve applicability and generalizability of findings'

Readmission Rates, Episode Costs Increased for Patients With Dementia

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Cost of 30-day readmission and total 30-day episode costs higher for patients with Alzheimer disease and related dementias

Risk for Neurodegenerative Disease Increased for Soccer Players

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Increased risk seen for Alzheimer disease and other dementias, but no increase seen for motor neuron disease or Parkinson disease

Less Postmortem Alzheimer Disease Pathology Seen With MIND, Mediterranean Diets

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Global Alzheimer disease pathology lower in patients following these dietary patterns, specifically less beta-amyloid load

Certain Genetic Variant in Alzheimer Disease Linked to African Ancestry

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Increased risk for Alzheimer disease and younger age of onset seen with APOE ε3 R145C missense variation

Social Isolation Tied to Wide Variety of Dementia Risk Factors

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Social isolation may be a modifiable risk factor for preventing Alzheimer disease-related dementias, authors say

Plasma Biomarkers Identified for Detecting Presymptomatic Alzheimer Disease

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Plasma P-tau181, NfL, GFAP concentrations higher in mutation carriers versus noncarriers of autosomal dominant Alzheimer disease

Vascular Risk Factors Only Explain Part of Alzheimer Disease Risk for Blacks, Hispanics

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Barriers to health care access and other socioeconomic factors may increase vulnerability in racial/ethnic minorities

PTSD, TBI Interact With APOE ε4 to Raise Alzheimer, Dementia Risk

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Significant additive APOE ε4 interactions seen with PTSD and TBI in veterans of European ancestry

FDA Approves Second Drug for Alzheimer Disease, Despite Safety Concerns

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Approval of Leqembi comes after controversial approval in 2021 of Aduhelm, which met with criticism over concerns about that drug's effectiveness, safety, pricing