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Implementation of Florida's Prescription Drug Monitoring Program and pill mill laws correlated with a modest reduction in opioid prescription and use

Drug Monitoring Program Tied to Drop in Opioid Rx in Florida

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Modest decrease in opioid prescriptions and use; reductions only in highest baseline prescribers, users
Early life adversity correlates with higher levels of internalizing symptoms and with altered brain structure

Early Life Adversity Linked to Brain Changes in Adolescent Boys

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Early life adversity linked to variation in brain structure directly and via internalizing symptoms
For individuals with normal and abnormal resting ankle-brachial index (ABI)

Post-Exercise ABI Expands Clinical, Prognostic Information

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Abnormal resting and post-exercise ABI linked to 2-fold increase in lower extremity revascularization
An approach for classifying pain severity developed by the Washington Group on Disability Statistics is effective for assessing self-reported pain among U.S. adults

Classification Details Pain Prevalence Among U.S. Adults

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6.4 percent of adults classified as having highest level of pain, based on persistence, bothersomeness
Excess postoperative mortality and morbidity is seen with use of guideline-based indications for mitral regurgitation surgery versus early surgery

Improved Outcomes With Early Mitral Regurgitation Surgery

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Surgical correction based on high probability of repair linked to improved survival
Among female high school field hockey players

Mandatory Eyewear Cuts Injuries in Girls’ Field Hockey

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National mandate for protective eyewear linked to reduced injuries in girls' high school field hockey
Smoking is a risk factor for clear cell and papillary renal cell carcinoma

Smoking Ups Risk of Some Renal Cell Cancer Histological Subtypes

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Higher risk for clear cell, papillary renal cell carcinoma, but not chromophobe histology
Data relating to the value of bedside physical examinations in the intensive care unit are sparse

Sparse Data Available on Value of Bedside Physical Exams in ICU

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Authors emphasize value of comprehensive physical examination in the ICU despite lack of data
Infection-related hospitalization during childhood is independently associated with adverse adult metabolic variables

Serious Childhood Infection Tied to Metabolic Disease Later in Life

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Early childhood hospitalization for infection tied to increased BMI, metabolic syndrome in adulthood
A drop in carbohydrate antigen 19-9 levels of more than 10 percent after two rounds of chemotherapy is associated with longer survival in patients with advanced pancreatic ductal adenocarcinoma

Antigen Level Signals Response to Chemo for Pancreatic Cancer

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Overall survival, time to progression longer with early drop of >10 percent in carbohydrate antigen 19-9