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Intravenous cyclosporine does not improve outcomes versus placebo in patients with anterior ST-segment elevation myocardial infarction who had been referred for primary percutaneous coronary intervention. The findings were published online Aug. 30 in the New England Journal of Medicine to coincide with the annual European Society of Cardiology Congress

Intravenous Cyclosporine Doesn’t Improve STEMI Outcomes

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For patients undergoing PCI, cyclosporine doesn't prevent adverse left ventricular remodeling at 1 year
The risk of osteonecrosis of the jaw is highest in association with intravenous bisphosphonate use

Osteonecrosis of Jaw Risk Highest for IV Bisphosphonate Use

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High risk for zoledronate, denosumab mainly in prevention of skeletal-related events
Femtosecond laser-assisted cataract surgery is associated with improved outcomes compared with conventional cataract surgery

Outcomes Up for Femtosecond Laser-Assisted Cataract Sx

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Significantly improved accuracy and repeatability of capsulorhexis compared with conventional sx
Recent research indicates that many pregnant women have a median urinary iodine concentration below the recommended level

Lack of Sufficient Iodine Nutrition Common During Pregnancy

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More targeted intervention strategies needed to optimize iodine nutrition during pregnancy
Nonalbuminuric chronic kidney disease is associated with increased risk of cardiovascular disease and all-cause mortality

Nonalbuminuric CKD Ups Cardiovascular Morbidity in T1DM

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Also linked to increase in all-cause mortality, but not albuminuria or end-stage renal disease
For patients with chronic fatigue syndrome

Multidisciplinary Rehab Tops CBT for Chronic Fatigue Syndrome

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Significantly more effective for reducing fatigue at 52 weeks versus cognitive behavioral therapy
In patients with type 1 diabetes

Periodontal Disease Predicts CAC Progression in Type 1 Diabetes

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No link with coronary artery calcium progression for individuals without diabetes
In patients with newly diagnosed multiple myeloma

Continuous Therapy Improves Survival in Multiple Myeloma

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Benefit seen in progression-free, overall survival compared with fixed duration of therapy
Physicians whose peers were early adopters of brachytherapy for the treatment of women with early-stage breast cancer are more likely to adopt the therapy themselves

Physicians’ Peers Influence Use of New Cancer Tx Modalities

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Exposure to peers who were early adopters of brachytherapy associated with increased use
Many health care providers don't follow guidelines meant to reduce the risk of infection from arterial catheter placement in intensive care unit patients

Low Adherence to Guidelines for Prevention of Catheter Infections

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Only 44 percent of health care providers said they follow CDC recommendations