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As monotherapy

Leukotriene Receptor Antagonist Monotherapy Ups Asthma Control

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Random effects meta-analysis shows reduced risk of exacerbation with LTRA monotherapy
The U.S. Preventive Services Task Force recommends that clinicians ask adults

USPSTF Urges Doctors to Ask Adults About Tobacco Use

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Clinicians should offer interventions to help adults, including pregnant women, stop smoking
The risk of developing diabetes is higher in younger adults versus middle-aged adults despite the same duration and degree of weight gain

T2DM Risk With Weight Gain Higher in Younger Adults

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Relative risk for same level of weight gain greater in younger adults than in middle-aged adults
Atrial fibrillation is associated with increased risk of dementia

Atrial Fibrillation Linked to Increased Risk of Dementia

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Association strongest for younger participants and for those with longest duration of AF
U.S. children with a genetic polymorphism affecting FUT2 secretor status appear to be protected from severe rotavirus gastroenteritis

Rotavirus Gastroenteritis Almost Absent in FUT2 Nonsecretors

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U.S. children with genetic polymorphism affecting secretor status seem to be protected from rotavirus
The Pioneer accountable care organization program correlated with reductions in low-value services during its first year

Accountable Care Organizations Can Cut Low-Value Service Use

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Greater reductions with higher than markets' mean baseline levels of low-value service use
Given its high cost

Regorafenib Deemed Not Cost-Effective for Metastatic CRC

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Findings based on its use as third-line treatment of metastatic colorectal cancer
Physicians

Docs in Productivity Models Likely to Encounter Compensation Caps

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Physicians, especially those working in a productivity model, must understand compensation caps
Obesity in adolescence is associated with changes in the circulatory T-lymphocyte profile

Teen Obesity Linked to Changes in T-Lymphocyte Profile

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Obesity linked to elevated absolute values of circulating CD3+ and CD4+ cells
Diffusion tensor imaging and cognitive assessment can identify predictive signs of hypertension-induced vascular cognitive impairment

New Imaging Technique Detects HTN-Linked Cognitive Impairment

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Findings for diffusion tensor imaging and cognitive assessment