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An ethical framework has been developed to guide the professionally responsible disclosure of results of genomic sequencing in pediatric practice. The guidance is presented in a special article published online Sept. 14 in Pediatrics.

Ethical Framework Developed for Genomic Testing Results

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Discussion of professionally responsible disclosure of results to parents and pediatric patients
Risk of autism spectrum disorder may be higher in children born after interpregnancy intervals of less than two years or greater than six years

Longer, Shorter Interpregnancy Interval Tied to Higher ASD Risk

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Higher autism risk seen in children born after <2-year or >6-year interval
For the 2010-2011 influenza season

No Increase in Febrile Seizures With 2010-2011 TIV or PCV13

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Also, no increased risk of febrile seizures for same-day versus separate-day vaccination
For children

Residential Pesticide Exposure May Raise Childhood Cancer Risk

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Increased risk of childhood leukemia and lymphoma seen with indoor insecticide exposure
Exercise has a positive effect on several measures of heart function as well as overall quality of life for patients with pulmonary hypertension

Exercise Appears Safe, Beneficial for Patients With Pulmonary HTN

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Meta-analysis of supervised exercise programs with lower levels of intensity
Clinicians should control hypertension much more aggressively than current guidelines suggest

NIH: Benefits for More Intensive Control of Hypertension

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Rates of heart attack, heart failure, and stroke cut significantly by more aggressive treatment
An initial attention-deficit/hyperactivity disorder diagnosis may be associated with delayed autism spectrum disorder diagnosis

Autism Diagnosis May Be Delayed With Co-Occurring ADHD

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Co-occurrence increases likelihood of autism diagnosis after age 6
Resveratrol and its major metabolites penetrate the blood-brain barrier to have central nervous system effects in patients with Alzheimer's disease

Resveratrol Impacts Central Nervous System Biomarkers

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High-dose oral resveratrol safe and well tolerated in Alzheimer's disease patients
Clinical practice guidelines on acute viral bronchiolitis vary in quality

Bronchiolitis Clinical Practice Guidelines Vary in Quality

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Highest scoring domains are 'score and purpose' and 'clarity of presentation'
For patients on warfarin

Anticoagulation Report Has Little Impact in Discharge Summary

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Safe Transitions Anticoagulation Report has no impact on clinical outcomes for patients on warfarin