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For patients with active ankylosing spondylitis

Secukinumab Cuts Symptoms of Ankylosing Spondylitis

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Two trials show benefits for 150 mg subcutaneous secukinumab with IV, subcutaneous loading
A single infusion of the potent human monoclonal antibody targeting the HIV-1 CD4 binding site

Infusion of HIV-Neutralizing Antibody Decreases Viremia

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Strong selection pressure seen for outgrowth of less neutralization-sensitive viruses
Comprehensive cigarette bans are most effective at limiting smoking among casual users

Both Smoking Bans and Cigarette Taxes Deter Smokers

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Bans seem better for social smokers; heavy smokers primarily deterred by taxes
Daylight photodynamic therapy with a novel variant of unsaturated ALA ester

Daylight Photodynamic Therapy Effective, Safe for Acne

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PDT with 1.5 percent 3-butenyl 5-aminolevulinate gel reduces inflammatory, non-inflammatory lesions
The number of births in the United States increased in 2014

CDC: Number of U.S. Births Up to 3.9 Million in 2014

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Decrease in rate of teenage pregnancies, and in birth rates for women in early 20s
For hospitalized patients

Daily INR Measurement Best for Hospitalized Patients on Warfarin

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Increased odds of warfarin-associated adverse events in patients for whom INR not measured daily
In a practice bulletin published in the January issue of Obstetrics & Gynecology

ACOG: New Recommendations for Cervical Cancer Screening

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Recommendations provide guidance on frequency of screening, appropriate screening methods
For patients undergoing percutaneous coronary intervention there has been an increase in use of mechanical circulatory support

Increase in Use of Mechanical Circulatory Support in PCI

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2004 to 2012 saw increase in percutaneous ventricular assist devices, intraaortic balloon pump
Experimental mood induction changes interleukin-18 levels and is associated with changes in central opioid neurotransmission

Experimental Mood Induction Impacts IL-18 Levels

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Experimental sadness increases IL-18, with changes more pronounced in depressed volunteers
For patients with angina pectoris

Ivabradine Improves Angina-Related Quality of Life

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No change in primary outcome of change in physical limitation score at 12 months