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Poor cardiovascular fitness and greater exercise blood pressure and heart rate responses in middle age correlate with smaller brain volume later in life

Cardiovascular Fitness, Exercise BP Linked to Brain Volume

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Poorer CV fitness, greater exercise BP in midlife linked to smaller brain volume 20 years later
The patient-centered medical home model of care seems to be contributing to decreases in costs and improvement in patient care

Medical Homes Contributing to Decreasing Cost of Care

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Patient-centered medical home model showing progress nationally; need for appropriate incentives
Elective colon resection is often performed after fewer than three previous episodes of uncomplicated diverticulitis

Early Surgery Common for Uncomplicated Diverticulitis

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More than half of elective resections done after fewer than three preceding episodes
The American Society of Clinical Oncology has updated recommendations on the use of biomarkers to guide decisions on adjuvant systemic therapy for women with early-stage invasive breast cancer. The clinical practice guideline was published online Feb. 8 in the Journal of Clinical Oncology.

ASCO Updates Biomarkers for Breast Cancer Tx Guidance

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Five assays show sufficient clinical utility, but don't guide specific regimens
Five genes may serve as biomarkers for osteoarthritis progression

Five Genes Tied to Osteoarthritis Progression

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Findings are potential biomarkers of osteoarthritic acetabular labrum
Treatment of exaggerated scars with dermal autologous micrografts appears effective

Dermal Autologous Micrograft May Be Effective Scar Treatment

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With further validation may be innovative regenerative treatment for scars
A multifaceted quality improvement initiative can cut laboratory costs in the hospitalist service of an academic medical center

Multifaceted QI Intervention Cuts Lab Costs

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Improvements seen in laboratory cost per day, per visit, and cuts in test per day
Mothers' vitamin B12 levels in early pregnancy may impact children's cardiometabolic risk factors at age 5 years

Maternal B12 Levels Impact Children’s Cardiometabolic Health

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Specifically, low folate levels seem tied to BMI, heart rate at age 5 years
Gastric bypass surgery is associated with improved long-term survival for patients at all ages above 35 years

Gastric Bypass Tied to Reduced Mortality for Obese >35 Years

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Lower mortality for patients aged 35 through 44, 45 through 54, 55 through 74 years
A novel Borrelia burgdorferi sensu lato genospecies has been identified

Novel Borrelia burgdorferi Sensu Lato Genospecies ID’d

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Species causes Lyme borreliosis in the United States; identified in six patients since 2012