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Health care professionals should use caution when prescribing the oral antifungal drug fluconazole (Diflucan) during pregnancy because it may raise the risk of miscarriage

FDA: Fluconazole Linked to Increased Miscarriage Risk

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Agency recommends alternatives to fluconazole for mothers-to-be until its review is complete
Preventive mastectomy that preserves the nipple and surrounding skin may be as effective in preventing breast cancer in high-risk women as more invasive surgeries

Nipple-Sparing Preventive Mastectomies Deemed Safe

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Preventive surgeries with nipple preservation don't appear to raise breast cancer risk in high-risk women
HIV-positive transplant recipients and their physicians should be aware of potential interactions between fixed dose combination products used for HIV treatment and immunosuppressant metabolism

Interactions for HIV Drug Combos, Immunosuppressants

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Drug interaction-induced calcineurin inhibitor nephrotoxicity described in renal transplant recipient
Neither the American College of Rheumatology nor the Systemic Lupus International Collaborating Clinics criteria distinguishes
patients with subacute cutaneous lupus erythematosus with major internal disease from those without

SLICC/ACR Criteria Don’t ID Severe Internal Disease in SCLE

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Clinicians should not rely on these criteria in subacute cutaneous lupus erythematosus
Simvastatin/ezetimibe does not appear to be beneficial for severe alopecia areata in a sample of 20 patients

Simvastatin/Ezetimibe Not Beneficial in Alopecia Areata

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In sample of 20 patients, most report no hair regrowth following six months of treatment
Treatment with the selective noradrenalin-reuptake-inhibitor atomoxetine is not associated with increased suicide risk compared with stimulant use in children and adolescents

Atomoxetine Use Doesn’t Up Suicide Risk in Children

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No increased risk for current atomoxetine use in first- and second-line treatment of youths
For patients undergoing transcatheter mitral valve repair

Six-Minute Walk Test Predicts Mortality in TMVR Patients

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For patients undergoing transcatheter mitral valve repair, highest mortality for those unable to walk
Detection of concerning symptoms after radical cystectomy can be improved by optimizing the timing and number of outpatient encounters

Optimally Timed Follow-Up Cuts Readmissions After Cystectomy

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Timing, frequency of outpatient care helps identify concerning symptoms following radical cystectomy
The drug eteplirsen should not be approved for treatment of Duchenne muscular dystrophy

FDA Panel Votes Against Approval of Eteplirsen for DMD

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Clinical data did not meet the agency's requirements for well controlled studies necessary for approval
Examining national data from 1999 through 2014

Severe Childhood Obesity Still on the Rise in the United States

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Treatment for these 4.5 million children is urgently needed