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Researchers say they've come closer to pinpointing genes linked with inflammatory bowel diseases such as Crohn's and ulcerative colitis. The research was published online June 28 in Nature.

Genes Responsible for Crohn’s, Ulcerative Colitis Identified

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Findings could improve efficacy of current treatments, lead to discovery of new drug targets
Depression is known to be linked to worsening physical health

Depression Contributes to Health Decline Seen in Cancer Caregivers

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Identifying signs early on might help protect these individuals, researchers say
For well-trained cyclists

EPO Doping Has Little Effect on Real-World Cycling Performance

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Appears to improve high-intensity performance, not endurance or road race performance
A novel nanoallergen platform has been developed

Nanoallergen Platform Can Identify Immunogenic Epitopes

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Novel platform can identify immunogenic epitopes in major peanut allergy protein, Ara h2
Immediate antiretroviral initiation at HIV diagnosis is associated with greater bone mineral density declines compared with deferred initiation

In HIV, Greater BMD Decline for Immediate Versus Delayed ART

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After one year, change in bone mineral density was similar in the immediate and deferred groups
For small skin abscesses

Clindamycin, TMP-SMX Linked to Better Outcomes for Abscesses

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Clindamycin or trimethoprim-sulfamethoxazole ups short-term outcomes vs incision, drainage alone
For children

Genetic, Environmental Exposure Tied to Islet Autoantibodies

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Link for male sex; father, sibling as diabetic proband; weight at 12 months with insulin autoantibodies
For adults with ischemic or nonischemic cardiomyopathy

ICD Treatment Cuts Sudden, All-Cause Death in Cardiomyopathy

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Reduction in rate of all-cause, sudden mortality for adults with ischemic, nonischemic cardiomyopathy
Pathologists can vary widely when assessing skin biopsies for melanoma

Melanoma Diagnoses Can Vary Widely Among Pathologists

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Potential for both overdiagnosis and underdiagnosis, patient confusion
A high IQ in childhood is associated with lower risk of mortality due to coronary heart disease and stroke

Higher IQ in Childhood Associated With a Longer Life

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Lifestyle choices may explain why children with a higher IQ tend to outlive their peers