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IgG-Degrading Enzyme Allows HLA-Incompatible Transplant

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IgG-degrading enzyme from Streptococcus pyogenes reduces, eliminates donor-specific antibodies

Are Clinicians Overprescribing Gabapentinoids for Pain?

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Non-trivial side effects, no robust evidence for off-label use of gabapentinoids for other types of pain

Less Than Half of Stroke Discharges Prescribed a Statin

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Prescribing differences by age, sex seen in 'Stroke Belt' in the southern U.S. versus rest of nation

FDA Approves Idhifa for Some With Acute Myeloid Leukemia

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For adults with relapsed or refractory AML who have an IDH2 genetic mutation

Downregulation of miR-126 Augments DNA Damage Response

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Reduced miR-126 levels in lungs from mice exposed to cigarette smoke, smokers' lung epithelial cells

TXNIP Blocks Autophagic Flux, Causes α-Synuclein Accumulation

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Thioredoxin-interacting protein plays important role in degeneration of dopaminergic neurons

Mechanisms ID’d for Curcumin Resensitization of Cancer Cells

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Compound helps turn off pathways linked to chemoresistance in pancreatic ductal adenocarcinoma

Review: Levetiracetam Best Monotherapy for Partial Seizures

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First-line tx sodium valproate tops carbamazepine, topiramate for generalized onset seizures

Inappropriate Med Use High in Cognitively Impaired Seniors

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Prevalence of potentially inappropriate medication use higher for frail seniors with cognitive impairment

Revenue Exceeds Expenditures for Many ABMS Member Boards

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Change in net balance of American Board of Medical Specialties member boards grew from 2003 to 2013