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Physicians consider the majority of ambulatory patients with advanced heart failure on medical therapy to be at high risk for transplant

Risk Assessment Differs for Doctors, Heart Failure Patients

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Doctors consider most patients with advanced heart failure to be at high risk for transplant, LVAD, death
The geriatric trauma outcome score II prognostic calculator can estimate the probability of unfavorable discharge in injured elders

Geriatric Trauma Outcome Score Estimates Unfavorable Discharge

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GTOS II estimates the probability of unfavorable discharge in injured elders with moderate accuracy
Antidepressant use is common among U.S. individuals aged 12 years and older

Antidepressants Used by 12.7 Percent of Those Age ≥12 in U.S.

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Use is higher among females than males; long-term use for one-fourth of those taking antidepressants
In non-alcoholic fatty liver disease

Plasma Amino Acids Up in Non-Alcoholic Fatty Liver Disease

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Ballooning/inflammation at liver biopsy linked to increased plasma branched chain, aromatic AAs
A single-color digital polymerase chain reaction assay can detect cancer mutations directly from circulating DNA from patients

Single-Color PCR Detects Cancer Mutations From Circulating DNA

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Mutation assays were developed specific to the cancer driver mutations of patients' tumors
From 2007 to 2014 there was a decrease in the proportion of patients needing dialysis after transcatheter aortic valve implantation

’07 to ’14 Saw Drop in Proportion Needing Dialysis After TAVI

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Need for new dialysis after TAVI linked to increased risk of mortality at 30-days and four years
A typical emergency department sees few cases of sepsis among adolescents

Emergency Departments See Few Cases of Sepsis in Adolescents

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Every 100 years, each of 12 emergency departments would treat 2.8 fatal sepsis cases
De novo KCNB1 missense and loss-of-function variants are associated with neurodevelopmental disorders

Phenotype Varies for Presumed Pathogenic Variants in KCNB1

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De novo mutations in KCNB1 associated with variable neurodevelopmental disorder
For pregnant women with pre-existing diabetes

Falling Insulin Requirement Linked to Placental Dysfunction

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FIR ≥15 percent linked to increased risk of composite of clinical markers of placental dysfunction
Neural network-based automated analyses of nocturnal oximetry recordings provide accurate identification of obstructive sleep apnea-hypopnea syndrome severity among habitually snoring children

Automated Analyses of Night Blood O2 Detects Apnea

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Findings for detection of sleep apnea among habitually snoring children