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Intensive systolic blood pressure lowering is associated with an increased risk of chronic kidney disease events but a reduced risk of cardiovascular events and mortality

Intensive BP Control Associated With Increased CKD Risk

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However, cardiovascular events, all-cause mortality risk decrease with intensive blood pressure lowering
For patients with uncontrolled asthma despite treatment with long-acting beta-agonists and medium-to-high doses of inhaled glucocorticoids

Reduced Asthma Exacerbations Seen With Tezepelumab

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Reduction seen with three dose levels of tezepelumab regardless of blood eosinophil counts
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Clinical Oral Food Challenges Result in Few Reactions

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86 percent of challenges result in no reactions; anaphylaxis absent in 98 percent
Tiotropium appears to be effective at improving lung function in patients with mild to moderate chronic obstructive pulmonary disease

Tiotropium Effective in Mild to Moderate COPD

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Daily inhaled dose tied to improvements in FEV1 compared to placebo
Implementation of a clinical pathway to improve care of acute gastroenteritis patients is associated with a sustained reduction in intravenous (IV) fluid use and length of stay in the pediatric emergency department

Intervention Beneficial for Acute Gastroenteritis Patients

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Reduction in IV fluid use and length of stay in pediatric ER after implementation of clinical pathway
For men with prostate cancer there is no difference in acute genitourinary or sexual dysfunction between 6- and 2-fraction high-dose-rate brachytherapy monotherapy

No Difference in Toxicity for 6-, 2-Fraction HDR in Prostate Cancer

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Urinary, sexual toxicity similar with 6-, 2-fraction high-dose-rate brachytherapy regimen
There is strong evidence that physical activity and a healthy diet reduce the risk of colorectal cancer

Strong Evidence for Healthy Lifestyle Reducing CRC Risk

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Consuming whole grains, foods with dietary fiber, dairy products reduces risk of colorectal cancer
A higher frequency of respiratory infections during the first two years of life is associated with an increased risk of celiac disease in genetically predisposed infants

Early Respiratory Infections Tied to Celiac in High-Risk Children

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More infections in first 24 months of life associated with higher risk of the disease
Alendronate treatment reduces the risk of hip fracture in elderly patients with a prior fracture

Alendronate Effective, Safe in ‘Oldest Old’ With Prior Fracture

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Alendronate treatment reduced risk of hip fracture with sustained safety
High rates of body dissatisfaction and disordered eating behaviors are reported by adolescents with type 1 diabetes

Many Teens With Type 1 Diabetes Report Disordered Eating

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Most also report body dissatisfaction, with females more likely to desire thinness