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The U.S. Preventive Services Task Force concludes that there is currently insufficient evidence to assess the benefits and harms of screening for peripheral artery disease with the ankle branchial index in asymptomatic adults. These findings form the basis of a final recommendation statement published in the July 10 issue of the Journal of the American Medical Association.

USPSTF: Evidence Lacking for ABI for PAD Screen in Asymptomatic

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No direct evidence, limited indirect evidence for benefits of PAD screening in asymptomatic population
Multivitamin/mineral supplementation seems not to be associated with cardiovascular disease outcomes

Taking Multivitamins/Minerals Doesn’t Improve CVD Outcomes

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MVM use not linked to decreased CVD mortality, CHD mortality, stroke mortality, or stroke incidence
Metformin use is associated with an increased risk of acidosis at estimated glomerular filtration rate <30mL/min/1.73 m²

Metformin Tied to Acidosis Risk at eGFR <30mL/min/1.73 m²

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Not linked to incident acidosis overall, in those with eGFR levels of 30 to 44, 45 to 59 mL/min/1.73 m²
Almost 3 percent of teenagers aged 13 to 18 years have food

Unhealthy Food Behaviors May Signal Eating Disorder in Teen

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Signs include restricting more and more food groups, significant weight change, excessive exercise
Early introduction of solids is associated with significantly longer sleep and less-frequent waking for infants

Early Introduction of Solids Linked to Better Infant Sleep

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Longer sleep duration, less frequent waking at night, and reduction in reported serious sleep problems
Use of electronic health record tools in isolation improves medication reconciliation but does not improve systolic blood pressure among patients with hypertension

EHR Tools Improve Medication Reconciliation in Hypertension

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However, systolic blood pressure did not differ in the EHR-plus-education group and usual care group
The attending surgeon is associated with variation in the receipt of genetic testing after breast cancer diagnosis

Attending Surgeon Influences Genetic Testing in Breast Cancer

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About one-third of surgeon variation explained by patient volume, surgeon attitudes to genetic testing
The incidence of treatment-emergent small-cell neuroendocrine prostate cancer (t-SCNC) is 17 percent among patients with metastatic castration-resistant prostate cancer

Advanced Prostate Cancer Variant More Common Than Thought

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Incidence of tx-emergent small-cell neuroendocrine prostate cancer 17 percent among those with mCRPC
An adverse impact on mental health is seen with reducing the age at which Lone Parent Obligations -- which require lone parents in the United Kingdom to seek work as a condition for receiving welfare benefits -- apply

Restricting Benefits for Single Moms May Harm Mental Health

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Requiring lone parents with young children to seek work as condition for benefits has adverse impact
Apixaban seems to be the safest direct oral anticoagulant compared with warfarin

Apixaban Is Safest Direct Oral Anticoagulant Versus Warfarin

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Reduced risks of major, intracranial, and gastrointestinal bleeding compared with warfarin