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A de-escalation from triple therapy to indacaterol/glycopyrronium may lead to a small reduction in lung function in non-frequently exacerbating patients with chronic obstructive pulmonary disease but no difference in exacerbations

Small Reduction in Lung Function With Tx De-Escalation in COPD

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No difference in exacerbations with indacaterol/glycopyrronium for non-frequently exacerbating COPD
How a situation is framed and the language used to describe risks can influence patients' decision-making

Situation Framing, Language Can Influence Decision-Making

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Docs should provide risks of both having treatment and not having treatment to minimize loss aversion
About 20.4 percent of U.S. adults have chronic pain and 8.0 percent have high-impact chronic pain

CDC: About One in Five U.S. Adults Have Chronic Pain

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Higher prevalence of chronic pain, high-impact chronic pain for women, older adults, rural residents
Including calorie count information on restaurant menus can result in a reduction in calories ordered

Including Calorie Count on Menus Can Cut Calories Ordered

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Exposure to calorie count increases consumers' support for requiring calorie labels
Users of valsartan contaminated with N-nitrosodimethylamine seem not to have increased cancer risk

No Apparent Short-Term Cancer Risk From Recalled Valsartan

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For single cancer outcomes, risk for colorectal, uterine cancer increased, but not significantly so
Newborns should not undergo universal sequencing at birth

Experts Advise Against Universal DNA Sequencing of Newborns

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Targeted, whole-exome or whole-genome sequencing can assist in diagnosis of symptomatic infants
Firearm deaths increased globally between 1990 and 2016

Firearm Deaths Up Globally From 1990 to 2016

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Variation among rates seen geographically and across demographic subgroups
Spreading oil and gas wastewaters on roads may pose human and environmental risks

Risks Posed by Spreading Oil and Gas Wastewater on Roads

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Nearly all of the metals from these wastewaters leach from the roads after rain events
Patients with chronic obstructive pulmonary disease with shorter telomere length have worse health status

Worse Health Status With Shorter Telomere Length in COPD

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Rate of exacerbation, risk of mortality up with shorter telomere length in placebo-treated patients
African-American patients are more likely to have prurigo nodularis

Prurigo Nodularis More Likely in African-Americans

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PN linked to chronic kidney disease, hepatitis C, congestive heart failure, HIV, psychiatric comorbidities