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March 2019 Briefing – Allergy

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Here are what the editors at HealthDay consider to be the most important developments in Allergy for March 2019. This roundup includes the latest...
There are many unanswered questions about the safety and effectiveness of a drug used to combat hallucinations and delusions in Parkinson disease patients

Questions Remain About Safety of Parkinson Disease Psychosis Drug

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Federal government has received high number of reports about deaths among patients taking Nuplazid
From 2012 to 2017

Perception of E-Cigarettes as More Harmful Than Cigarettes Increased

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Increase observed in proportion who see e-cigarettes to be as harmful as, more harmful than cigarettes
A higher prenatal omega-6:omega-3 long chain polyunsaturated fatty acid ratio in cord plasma is associated with a higher attention-deficit/hyperactivity disorder index score for the child at age 7 years

High Prenatal Omega-6:Omega-3 Ratio Linked to ADHD at Age 7

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Higher prenatal n-6:n-3 ratio in cord plasma linked to a higher ADHD score at age 7 years, but not at age 4
Higher disease activity

Patients With Worse RA Symptoms More Likely to Cut Alcohol Intake

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No evidence found that alcohol use has beneficial effect in rheumatoid arthritis patients
Therapeutic ball pits in physical therapy clinics may pose an infection hazard

Therapeutic Ball Pits Found to Harbor Pathogenic Germs

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Ball pits show wide variability in microbial colonization of infection-causing microorganisms
Based on active surveillance data of acute respiratory illness

CDC: 2017 to 2018 Saw Increase in Enterovirus D68 Detection

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EV-D68 detected in 13.9 percent of patients with acute respiratory illness in 2018
Patients taking phentermine for weight loss for more than three months experience greater weight loss without an increased risk for incident cardiovascular disease or death

Long-Term Phentermine Use Safe, Effective for Weight Loss

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No difference in cardiovascular disease, death seen between those taking the drug for >12 versus ≤3 months
Intake of omega-3 and omega-6 is associated with pediatric asthma morbidity and may modify the response to indoor particulate matter

Dietary Fatty Acid Intake Linked to Pediatric Asthma Morbidity

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Omega fatty acid intake also modifies effect of indoor PM exposure on respiratory symptoms
Varied study design and methodology make it difficult to assess real-world trends in adherence and persistence in use of biologics among U.S. adults with inflammatory bowel disease

Use of Biologics to Treat IBD in U.S. Adults May Be Suboptimal

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While study design, methodology make comparisons difficult, adherence, continuation appear to be poor