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Expert guidance has been provided on the early detection of colorectal cancer and on treatment and posttreatment follow-up; the two guidelines were recently published online in the Journal of Global Oncology.

ASCO: Guidelines Released for Early Detection, Treatment of CRC

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Stratified guidelines emphasize optimal detection methods and treatments of colorectal cancer
Testosterone therapy can prevent progression to type 2 diabetes in men with prediabetes and hypogonadism

Testosterone Therapy in Hypogonadism Can Prevent Progression to T2DM

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Men with prediabetes, hypogonadism achieved normal glucose regulation with TTh
Recommendations have been developed for use of polymyxins

Guidelines Developed for Polymyxin Antibiotic Use

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Polymyxin B recommended for routine use in invasive infections; colistin preferred for lower UTI
The robotic stereoelectroencephalography procedure to determine whether patients with pharmacoresistant epilepsy are candidates for brain surgery is safer and more efficient and more often leads to favorable epilepsy outcomes than the traditional subdural electrode implantation method among those undergoing resection or ablation

Less Invasive Method Safely IDs Epilepsy Surgical Candidates

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Stereoelectroencephalography has better outcomes than subdural electrode implants in some cases
An archetypal approach can identify the diagnostic and prognostic features associated with transplant glomerulopathy

Risk Profiles ID’d for Patients With Transplant Glomerulopathy

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Five groups of patients with distinct features and outcomes identified using machine learning approach
Of patients diagnosed with osteoporosis who have a history of hip fracture

AAOS: Supplement Use Low in Patients With Osteoporosis, Hip Fracture

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Non-Caucasian minorities less likely to receive proper supplementation
There has been a steady rise in mood disorder and suicide-related outcomes among individuals born from the early 1980s to the late 1990s

Mental Health Issues Have Risen in Teens, Young Adults

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Rates of depressive episodes, serious psychological distress, suicide-related outcomes have increased
Many providers stopped initiating opioid therapy from July 2012 to December 2017

Opioid Prescriptions Dropped for New Users From 2012 to 2017

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Decline seen in number of providers initiating opioid therapy in any patients who have not used opioids
There may be a small benefit to labor induction in low-risk woman at 41 weeks versus expectant management

Induction for Late-Term Pregnancies at 41 Weeks Tied to Small Benefits

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Study could not show noninferiority of expectant management; outcomes good with both strategies
Authors of a paper recently published in the Journal of the American Geriatrics Society describe factors that influenced the new National Institute of Health policy that requires funded scholars to eliminate arbitrary age limits in their work.

Influences on New NIH Policy for Age Limits in Research Explored

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'Inclusion Across the Lifespan' policy eliminates non-risk-justified age limits on research participants