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Lumacaftor/ivacaftor treatment is generally safe and well tolerated for children aged 2 to 5 years with cystic fibrosis homozygous for the F508del-CFTR mutation

Drug Combo Tolerated in Younger Children With Cystic Fibrosis

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Lumacaftor/ivacaftor safe in children ages 2 to 5 with cystic fibrosis homozygous for F508del-CFTR
The benefits of postconditioning balloon inflations in patients with ST-segment-elevation myocardial infarction undergoing percutaneous coronary intervention may not be apparent immediately

Postconditioning During PCI for STEMI Shows Delayed Benefits

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Benefits at one year include reduced microvascular obstruction, improved left ventricular remodeling
Cablivi (caplacizumab-yhdp) injection has been approved by the U.S. Food and Drug Administration to treat adults with acquired thrombotic thrombocytopenic purpura.

FDA Approves Cablivi for Rare Blood-Clotting Disorder

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Drug approved to treat adults with acquired thrombotic thrombocytopenic purpura
Preliminary results from a patient being tested for Ebola suggest that the patient has another condition

Patient Tested for Ebola at Philadelphia Hospital

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Testing was done out of 'an abundance of caution'
For older adults undergoing surgery

EEG-Guided Anesthesia Does Not Cut Postop Delirium in Seniors

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Significantly less median cumulative time found with EEG suppression in EEG-guided group vs. usual care
Recommendations have been updated for tonsillectomy in children; the revised clinical practice guideline was published as a supplement to the February issue of Otolaryngology-Head and Neck Surgery.

Recommendations Updated for Tonsillectomy in Children

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Strong recommendations presented against administering perioperative antibiotics, codeine after tonsillectomy
Omadacycline is noninferior to moxifloxacin for community-acquired bacterial pneumonia and noninferior to linezolid for acute bacterial skin infections

Omadacycline Noninferior to Moxifloxacin for Pneumonia

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Second study shows noninferiority to linezolid for acute bacterial skin and skin-structure infections
Federal value-based incentive programs are not associated with reductions in device-associated catheter-associated urinary tract infection rates

Value-Based Incentive Program Does Not Cut Catheter-Linked UTIs

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VBIP implementation not linked with immediate changes or changes in trends for any outcome
Irrespective of age and weight

Type 2 Diabetes Risk Up With PCOS Regardless of BMI

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PCOS one of most influential predictors of T2DM after adjustment for BMI, education, family history
Implementation of a novel enhanced recovery after surgery protocol can reduce patients' postoperative opioid requirements after elective spinal or peripheral nerve surgery

ERAS Protocol Can Cut Opioid Use After Spine Surgery

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Decline seen in postoperative opioid requirements after elective spinal, peripheral nerve surgery