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Overuse of broad-spectrum antibiotics is associated with increased mortality and other poor outcomes in adults admitted for community-onset pneumonia

Poor Pneumonia Outcomes Tied to Overuse of Broad-Spectrum Antibiotics

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Poor outcomes include higher mortality, longer hospital stay, and greater risk for C. difficile infection
Among patients hospitalized for acute coronary syndrome

High-Intensity Lipid Lowering May Aid Very Elderly After ACS

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Benefit of simvastatin-ezetimibe combo after acute coronary syndrome greatest for patients ≥75 years
A DNA methylation classifier can predict progression in young women with untreated cervical intraepithelial neoplasia grade 2

DNA Methylation Classifier Predicts Progression in CIN2

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For regression versus progression outcome, highest AUC was 0.735 for combination of S5, cytology
Evidence shows that vaccination is not associated with an increased risk for being diagnosed with multiple sclerosis within the next five years

Vaccination Does Not Up Risk for Developing Multiple Sclerosis

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Odds of MS lower in participants with vaccination, especially for influenza, tick-borne illness
Transdermal optical imaging can be used to predict systolic

Transdermal Optical Imaging Shows Promise for Measuring BP

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Models could predict systolic, diastolic, pulse pressure within 5 ± 8 mm Hg of reference measurements
More than half of randomized controlled trials with statistically nonsignificant findings for the primary end points published in psychiatry and psychology journals have spin in the abstract

Reporting of Results Often Biased in Psychiatry, Psychology Trials

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Fifty-six percent of trials had spin in abstract; no correlation seen for industry funding with spin
For hyperglycemic adults with diabetes

Lifestyle Counseling Frequency, CV Outcomes Linked in Diabetes

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More frequent counseling tied to lower incidence of death, CV events in adults with diabetes
Incorporating focused cardiac ultrasonography into clinical examination has greater sensitivity

Low Specificity Limits Use of Focused Cardiac Ultrasonography

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FoCUS may help rule out ventricular dysfunction, valvular disease in low-risk patients
Patient outcomes may not be better at top-ranked hospitals for common advanced laparoscopic abdominal operations

Ranking for Abdominal Surgeries Not Linked to Patient Outcomes

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Serious morbidity, in-hospital mortality similar for laparoscopic sx at top-ranked, nonranked hospitals
There were significant increases in infant mortality from accidental suffocation and strangulation in bed from 1999 to 2016

Infant Suffocation Deaths in Bed Increased From 1996 to 2016

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Rates higher for non-Hispanic black infants versus whites, although risk factors the same