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Sotagliflozin

Addition of Sotagliflozin for T1DM Alters Renal Hemodynamics

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Addition of SOTA tied to reductions in estimated glomerular filtration rate, blood pressure
For women with intrahepatic cholestasis of pregnancy

Common Therapy for Obstetric Cholestasis Found Ineffective

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Treatment with ursodeoxycholic acid versus placebo yielded no significant difference in outcome
Diets higher in plant-based foods and lower in animal-based foods are associated with lower risks for developing or dying from cardiovascular disease among middle-aged adults

Plant-Based Diets May Lower CV Disease, Deaths in Middle-Aged

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Association also found for reduction in all-cause mortality but not incident cardiovascular disease
In an official American Thoracic Society clinical practice guideline

Recommendations Developed for Obesity Hypoventilation Syndrome

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Interventions producing sustained weight loss of 25 to 30 percent of body weight recommended
Preterm infants

Completion Rates of Recommended Vaccines Lower for Preemies

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Rate of completion lower for seven-vaccine series by 19 months and 36 months of age
Stroke patients discharged with a case manager and access to an educational website report significantly greater improvements in physical health after three months compared with those who receive traditional care

At-Home Support Helps Stroke Patients Adjust After Hospitalization

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Home-based support network includes social work case managers and online resources
Spending associated with essential medicines grew substantially from 2011 to 2015 for Medicare Part D beneficiaries

Medicare Spending on Essential Medicines Up 116 Percent From 2011 to 2015

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22 percent of increased total spending due to higher per-unit cost of existing drugs
From 2012 to 2018

2012 to 2018 Saw Substantial Rise in Naloxone Dispensing

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Regional variation in naloxone dispensing considerable; rates lowest in most rural counties
Exercise during pregnancy may improve early neuromotor development of infant offspring

Exercise During Pregnancy May Boost Infant Development

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Higher neuromotor scores seen in infants at 1 month of age
The U.S. Preventive Services Task Force recommends against screening for pancreatic adenocarcinoma as the potential benefits do not outweigh the potential harms. These recommendations form the basis of a final recommendation statement published in the Aug. 6 issue of the Journal of the American Medical Association.

USPSTF Reaffirms Recs Against Screening for Pancreatic Cancer

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Potential benefits of screening do not outweigh potential harms in asymptomatic adults