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Bumetanide seems effective for improving symptoms of autism spectrum disorder in young children

Bumetanide Promising for Reducing Autism Symptoms

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Decrease in GABA/glutamate ratio in insular cortex tied to symptom improvement in bumetanide group
Major depressive disorder and noncombat trauma are important factors tied to suicide ideation risk during combat deployment

More Than One in 10 Deployed Soldiers Thinks About Suicide

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Lifetime noncombat trauma exposure and major depressive disorder may up the risk for suicide ideation
In children with fragile X syndrome

Atypical Sleep Tied to Language Skills in Neurodevelopmental Disorders

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Nighttime sleep duration predicted receptive vocabulary size in Down syndrome, Williams syndrome
Patients with rhinitis who live in high-pollution areas are more likely to report severe nasal symptoms

Higher Pollution Levels May Up Severity of Rhinitis Symptoms

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Increased levels of PM10, PM2.5 tied to higher levels of severity, with exposure-response relationship
Multiple major cities in China are estimated to have imported cases of 2019 novel coronavirus and epidemics are estimated to be growing exponentially in those cities

Spread of 2019 Novel Coronavirus Outbreak Estimated

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By Jan. 25, 2020, 75,815 individuals had been infected in Wuhan; epidemic doubling time 6.4 days
In a clinical guideline published online Feb. 4 in the Annals of Internal Medicine

U.S. Adult Immunization Schedule Updated for 2020

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Shared clinical decision making recommended for HPV in adults age 27 to 45 considered likely to benefit
Altering the default settings in the electronic medical record can influence the quantity of opioids prescribed in an emergency department setting

Altering Default Settings in EHR Influences Opioid Prescribing

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Lower default was associated with lower number of pills prescribed in eight of 15 pairwise comparisons
A clinical trial to test an experimental antiviral drug's effectiveness against the new coronavirus will be conducted in China as it battles a coronavirus outbreak there.

Experimental Antiviral Drug to Be Tested Against New Coronavirus

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Trial to be conducted in the central Chinese city of Wuhan, the epicenter of the outbreak
A clinical trial for an HIV vaccine has been halted after it was concluded that it did not prevent infection with the AIDS-causing virus

HIV Vaccine Ineffective, Clinical Trial Halted

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NIH-sponsored trial was being conducted in South Africa

January 2020 Briefing – Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for January 2020. This roundup includes the latest...