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Inhibition of sclerostin with romosozumab may increase cardiovascular risk

Inhibition of Sclerostin May Increase Cardiovascular Risk

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SOST genetic variants linked to lower risk for fracture and osteoporosis but higher risk for MI, major CV AEs
It is possible to predict the likelihood of testing positive for COVID-19

Model May Help Predict Risk for Testing Positive for COVID-19

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Risk reduced with pneumococcal polysaccharide, flu vaccine; melatonin, paroxetine, or carvedilol use
The prevalence of metabolic syndrome among young adults in the United States is rising

Metabolic Syndrome Up in Young Adults in the United States

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Significant increases between 2011 and 2016 also seen for women, Asians, and Hispanics
Triple therapy

Triple Inhaled Therapy Aids in Moderate-to-Very Severe COPD

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Benefit seen for twice-daily triple inhaled therapy with glucocorticoid, glycopyrrolate, formoterol
Factors readily available in administrative data can predict five- and 10-year mortality in older adults with diabetes

Administrative Data Predict Mortality With Diabetes

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Thirty-seven factors have good accuracy for predicting five- and 10-year mortality in older veterans
The U.S. burden of skin and subcutaneous diseases is large but varies geographically

U.S. Burden of Skin and Subcutaneous Diseases Increasing

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Increases seen across all 50 states, with geographic variation in percentage
Bayer has agreed to pay more than $10 billion to settle thousands of U.S. lawsuits alleging that its weedkiller Roundup causes cancer.

Bayer to Pay $10 Billion to Settle Roundup Lawsuits

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Amount includes $1.25 billion for potential future claims from people who used Roundup
French drugmaker Sanofi has shortened its timeline to get a COVID-19 vaccine on the market.

Sanofi Speeds COVID-19 Vaccine Efforts

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Company says it may be able to get a vaccine approved by regulators as early as the first half of 2021
Johnson & Johnson and a subsidiary must pay $2.1 billion in damages to women who said their ovarian cancers were caused by the company's baby powder and other talcum products

J&J Ordered to Pay $2.1 Billion in Talcum Product Lawsuit

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Decision reduced by more than half the record award of $4.7 billion made to the women in July 2018
An outbreak of Cyclospora infections in the U.S. Midwest appears to be linked to bagged salad mixes

Cyclospora Outbreak Linked to Bagged Salad Mixes

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19 people have been hospitalized; no deaths reported