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New drug applications for prescription opioids for pain have been based on pivotal trials of short or intermediate duration

New FDA Applications for Opioids Often Based on Short Trials

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Most products for treating chronic pain approved based on narrowly defined populations of patients
None of 54 patients hospitalized with COVID-19 with in-hospital cardiac arrest who underwent cardiopulmonary resuscitation survived to discharge

Outcomes of In-Hospital Cardiac Arrest Poor in COVID-19 Patients

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Of the 54 patients receiving CPR who were included in the analysis, none survived to discharge
Survivors of childhood cancer have a lower prevalence of suicidal behaviors and mortality

Suicidal Behaviors, Deaths Lower for Childhood Cancer Survivors

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But prevalence of suicidal ideation similar for childhood cancer survivors, general population
The presence of a brain-eating amoeba in its drinking water has led the city of Lake Jackson

Brain-Eating Amoeba Found in Tap Water of Lake Jackson, Texas

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Infection can occur when Naegleria fowleri-contaminated water enters body through the nose
A company has agreed to pay $60 million to settle charges by U.S. state attorneys general that it failed to adequately inform women of dangerous side effects associated with permanent pelvic mesh devices.

Company Pays $60 Million to Settle Pelvic Mesh Case

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Payment will be shared by 48 states and the District of Columbia
During 2018

Private Health Plans Pay Hospitals 247 Percent of Medicare

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Relative prices average 231, 267 percent of what Medicare would pay for inpatient, outpatient services
Vitamin D sufficiency is associated with reduced clinical severity

Clinical Severity Lower With Vitamin D Sufficiency in COVID-19

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Of patients aged ≥40 who died, 9.7 percent were vitamin D-sufficient versus 20 percent with 25(OH)D <30 ng/mL
Fewer than 10 percent of the U.S. adult population formed antibodies against severe acute respiratory syndrome coronavirus 2 during the first wave of the pandemic

<10 Percent of U.S. Population Has Antibodies to SARS-CoV-2

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Comparing seroprevalence and case counts shows only 9.2 percent of seropositive patients diagnosed
In a genome-wide association study

14 Novel Loci Identified for Abdominal Aortic Aneurysm

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Genetic increase of 10 mm Hg in diastolic blood pressure likely has causal link with AAA
Infants born to mothers testing positive for severe acute respiratory syndrome coronavirus 2 do not have a higher frequency of adverse outcomes than those born to mothers testing negative

Infants of COVID-19-Infected Mothers Doing Well in Short Term

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No differences seen in rates of preterm birth, NICU admission, respiratory disease with infection