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Higher cumulative exposure to antibiotics is associated with an increased risk for new-onset inflammatory bowel disease

Antibiotic Exposure Linked to Risk for Inflammatory Bowel Disease

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Patients receiving one, two, three or more antibiotic dispensations have increased odds of IBD
For patients with homozygous familial hypercholesterolemia

Evinacumab Cuts LDL-C Level in Familial Hypercholesterolemia

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LDL-C down at week 24 with evinacumab versus placebo in homozygous familial hypercholesterolemia
Longer duration of bisphosphonate use is associated with an increased risk for atypical femur fracture

Longer Bisphosphonate Use May Up Atypical Femur Fracture Risk

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Rapid decline in atypical fracture risk seen when bisphosphonate discontinued in women ≥50 years
Children with severe acute respiratory syndrome coronavirus 2 infection have the highest nasopharyngeal viral load in the first two days of symptoms

SARS-CoV-2 Nasopharyngeal Load Higher in Children Than Adults

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Highest viral load seen in the first two days of symptoms in children with SARS-CoV-2 infection
Alzheimer disease (AD) may causally influence sleep patterns

Relationship Between Alzheimer Disease, Sleep Patterns Explored

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No evidence supporting causal role of disturbed sleep patterns on AD or between major depression and AD
Increased adherence to alternate Mediterranean and Alternative Healthy Eating Index dietary patterns is inversely associated with prodromal features of Parkinson disease

Healthy Diet Inversely Linked to Prodromal Parkinson Disease Features

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Adherence to aMED, AHEI dietary patterns inversely tied to constipation, daytime sleepiness, depression
There are considerable disparities in the prevalence of COVID-19 across racial/ethnic subgroups in the United States

Disparities Seen in COVID-19 Hospitalizations in Racial/Ethnic Subgroups

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Percentage of hospitalizations among Black patients exceeded percent in the state population
Each additional week of alcohol exposure during the first trimester of pregnancy increases the risk for spontaneous abortion

Each Week of Early Alcohol Use Tied to Incremental Miscarriage Risk

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Risk increased even at low levels of consumption and when excluding binge drinking in first trimester
Preexposure prophylaxis is well tolerated by men who have sex with men at episodic risk for HIV while on vacation

Short-Term PrEP Feasible for Men at Risk for HIV on Vacation

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High levels of medication adherence observed; many interested in transitioning to long-term PrEP
Baby boomer caregivers more often have chronic health conditions and frequent mental distress than noncaregivers

Health Worse for Baby Boomer Caregivers Versus Noncaregivers

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More caregivers have at least one chronic health condition, more often have frequent mental distress