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Lecanemab for Alzheimer Disease Safe, Feasible in Real-World Practice

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Patients in the earliest stage of Alzheimer disease, with very mild symptoms, experienced the lowest risk of complications

Some Triple Negative Breast Cancers Might Be Avoided by Longer Breastfeeding

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Authors say policy changes that support breastfeeding and address structural barriers are needed

Risk of Obesity-Related Cancer Similar for GLP-1 Receptor Agonists and Bariatric Surgery

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Findings for matched groups of patients with obesity and diabetes taking first-generation GLP-1 RA or undergoing bariatric metabolic surgery

Gabapentinoids Not Directly Associated With Risk of Self-Harm

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However, increased risk of self-harm is seen before initiation of treatment, during initial phase of treatment, and after discontinuation

AAP Updates Guidance on Evaluation, Treatment of Patent Ductus Arteriosus in Preemies

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Medical closure using ibuprofen or acetaminophen is an option for hemodynamically significant patent ductus arteriosus

Risk of Poor Cardiovascular Outcomes Up in Aging Patients With Down Syndrome

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Higher stroke risk seen overall, and higher risk of acute myocardial infarction seen in those with Down syndrome under 40 years of age

Preinjury Mobility Predicts Adults’ Recovery After Lower-Extremity Fracture

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Findings from a proof-of-concept study using patients' smartphone mobility data

Exercise May Provide Protection for Childhood Psychiatric Conditions

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No protective associations seen for time outdoors, but protective effects for participation in organized sports

No Link Found Between COVID-19 Vaccination During Pregnancy and Spontaneous Abortion

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Authors say findings confirm safety of COVID-19 vaccine during pregnancy

More Research Needed to Prepare People With Mental Illness for Menopause

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Review only identifies a few studies assessing psychoeducation intervention in those with depression or bipolar disorder