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The 2015 version of the American Board of Internal Medicine maintenance-of-certification program is expected to generate considerable costs

2015 MOC Program Expected to Cost $5.7 Billion Over 10 Years

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Time costs account for 90 percent of maintenance of certification costs, estimated at $5.1 billion
For patients with non-ST-segment elevation acute coronary syndrome

Early Invasive Strategy No Benefit 10 Years After NSTE-ACS

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No improved outcomes versus selective invasive strategy in non-ST segment acute coronary syndrome
The recently developed RAPID score

RAPID Score Validated for Prognosis of Pleural Infections

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Recently developed score is valid for identifying mortality risk through five years in diverse cohort
A novel

Novel Microendoscope Ups Accuracy of Esophageal Screening

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Low-cost HRME ups accuracy of Lugol's chromoendoscopy for esophageal cancer
For canagliflozin-treated patients with type 2 diabetes

Low Incidence of Diabetic Ketoacidosis With Canagliflozin

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Canagliflozin-treated patients with type 2 diabetes have low incidence of serious adverse DKA events
Topical retinoid exposure is not significantly associated with an increased risk of major congenital malformations

No Significant Pregnancy Risks for Topical Retinoid Exposure

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No significantly increased risk of major congenital malformations, spontaneous abortion, prematurity
For polytraumatized patients

Early Surgery Tied to Increased Mortality in Polytraumatized

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High mortality rates in patients with concomitant severe thoracic trauma and low initial Hb
Continuous and intermittent administration of β-lactam antibiotics are similarly efficacious for patients with severe sepsis

Outcomes Equal for Continuous, Intermittent β-Lactams in Sepsis

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No differences in ICU-free days, 90-day survival, organ failure-free days, bacteremia duration
The selective Hedgehog antagonist PF-04449913 seems safe and is tolerated in adults with myeloid malignancies

New Rx for Myeloid Malignancies Moves to Phase II Clinical Trials

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Phase I trial involving 47 patients identified maximum tolerated dose of 400 mg once daily
For patients with neural foraminal or lateral recess stenosis with unilateral leg neurogenic symptoms

No Lasting Value for Minimally Invasive Lumbar Laminotomy

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No differences or improvement in back or leg pain, ODI, neurogenic symptoms, SF-36 scores