Archives
Circulating Tumor HPV DNA Can ID HPV+OPSCC Years Before Diagnosis
Sensitivity of detection increased to 96 percent; maximum lead time increased to 10.3 years with application of machine learning model
PM2.5 Exposure Linked to Increased Dementia Severity
Higher PM2.5 exposure prior to death linked to increased odds of more severe Alzheimer disease neuropathologic change
Radiation Exposure From Medical Imaging Linked to Hematologic Cancer Risk in Children
10.1 percent of hematologic cancers in this cohort may have been attributable to radiation exposure from medical imaging
Aspirin Linked to Lower CRC Recurrence for Molecularly Defined Subgroup
Significantly lower incidence of colorectal cancer recurrence seen for patients with somatic alterations in PI3K pathway genes
Neonatal Male Circumcision Rates Reduced From 2012 to 2022
Findings seen despite 2012 American Academy of Pediatrics guidance in support of the practice
Model Based on Mammogram Features, Age Can Predict CV Risk
DeepSurv model using mammography features and age has similar performance to modern models
Surgical Volume Increases With Introduction of HoLEP
Surgical volume increased significantly after adoption of holmium laser enucleation of the prostate, with no change in catchment area
Once-Weekly Semaglutide 7.2 mg Beats Placebo for Obesity
Second study shows 7.2 mg semaglutide leads to greater reductions in mean body weight for those with obesity, T2D
Evidence Insufficient to Determine Benefits of Multicancer Screening Tests
Sensitivity ranged from 0.095 to 0.998; specificity from 0.657 to 1.0; AUC from 0.52 to 1.0 across tests
Acupuncture Beneficial for Chronic Low Back Pain in Older Adults
Significantly better change scores seen in Roland-Morris Disability Questionnaire at six and 12 months with acupuncture versus usual care
