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Daratumumab monotherapy has a favorable safety profile and encouraging efficacy in patients with heavily pretreated and refractory myeloma in a phase 1-2 trial. The results of the study were published online Aug. 26 in the New England Journal of Medicine.

Daratumumab Monotherapy Promising for Multiple Myeloma

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Findings in a phase 1-2 study of patients with relapsed myeloma or relapsed/refractory myeloma
For most atrial fibrillation patients taking warfarin who require temporary interruption for a procedure

Periop Bridging Unnecessary for Most A-Fib Patients on Warfarin

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Arterial thromboembolism risk doesn't appear to rise without additional drug treatment
Tadalafil (Cialis) combined with ambrisentan (Letairis) significantly reduces the progression of pulmonary arterial hypertension

Cialis Combo Rx Aids Treatment of Pulmonary Arterial HTN

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Combining tadalafil, blood pressure med helped patients with pulmonary arterial hypertension
Microfocused ultrasound appears safe for improving laxity of the skin of the face and neck in patients with Fitzpatrick skin types III to VI

Microfocused Ultrasound Safe for Fitzpatrick Skin Types III-VI

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Three reported adverse events were temporary and associated with treatment technique
Severe liver damage may be four times more common among Americans with hepatitis C than previously believed

Cirrhosis in Hepatitis C More Widespread Than Thought

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Biopsy alone greatly underestimates prevalence, researcher says
Antiviral drugs may help protect people from developing Ebola after exposure to the virus

Antiviral Rx May Help Prevent Ebola, Small Study Suggests

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Health care workers on antiviral regimen didn't develop disease after exposure
A majority of women who receive false positives on mammography experience distress and anxiety

Most Women Feel Distress With False-Positive Mammogram

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Majority had issues such as anxiety, sleeplessness, often persisting long after being declared cancer-free
Gay and bisexual adolescent boys are much less likely to get tested for HIV than their older counterparts

Low Rates of HIV Testing in Gay and Bisexual Youth

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Only one in five gay and bisexual males ages 14 to 18 had ever been tested for HIV
The potential effect of cannabis on brain structure remains a subject of intense scientific scrutiny

Mixed Results for Cannabis Effect on Developing Brain

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One of two new studies suggests cannabis use in teen years might be more harmful for males
Lung microbiomes are similar in patients with and without HIV

Lung Microbiome Similar With/Without HIV

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No relationship seen between CD4 counts and microbiome data