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Obesity enhances local myofibroblast content and stiffness-promoting extracellular matrix components in mammary adipose tissue

Obesity May Fuel Breast CA Via Change in Breast Tissue Structure

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Findings suggest obesity can trigger structural changes in extracellular matrix
For some

BRAF V600 Is Targetable in Some Nonmelanoma Cancers

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Vemurafenib active in NSCLC, Erdheim-Chester disease, Langerhans'-cell histiocytosis
Working long hours is associated with increased risk of stroke

Long Work Hours Linked to Increased Risk of Stroke

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Association with coronary heart disease is smaller; dose-response association seen for stroke
Oral contraceptive exposure is associated with better patient-reported outcomes in early inflammatory arthritis

Oral Contraceptive Use May Moderate Inflammatory Arthritis

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OC use linked to better Rheumatoid Arthritis Impact of Disease scores over two years
There is considerable variation in the unit cost of topical corticosteroids across potencies and by branded generic or generic product

Considerable Variation in Cost of Generic Topical Corticosteroids

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Variation in cost seen across potencies, class, and by branded generic or generic product
In a practice bulletin published in the September issue of Obstetrics & Gynecology

ACOG: Best Evidence for Rx of Nausea, Vomiting in Pregnancy

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Vitamin B6 or vitamin B6 plus doxylamine is safe and effective; recommended for first-line tx
For patients with type 2 diabetes

Long-Acting Analog Insulin Doesn’t Up AMI Risk in T2DM

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No significant difference in risk for long-acting analog, other basal insulin therapies
Use of patient navigators as inpatient care facilitators shortens hospital length of stay

Patient Navigators Tied to Shorter Hospital Stays

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Use of patient navigators on general medical service didn't affect readmissions
For hospitalized patients

Peripherally Inserted Central Catheters Up VTE Risk

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In hospitalized patients, increased risk of upper- and lower-extremity deep vein thrombosis
Acetaminophen falsely increases continuous glucose monitor glucose values

Acetaminophen Falsely Elevates CGM Glucose Values

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CGM glucose values increased versus blood glucose meter values in acetaminophen challenge