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Imetelstat

Imetelstat Deemed Active in Myelofibrosis, Thrombocythemia

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Responses for patients with myelofibrosis, essential thrombocythemia
There has been an increase in the number of American men with cancer in one breast who have surgery to remove their cancer-free breast

More Male Breast CA Patients Having Both Breasts Removed

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Trend mirrors the one seen in women, researchers say
An experimental therapy for chronic lymphocytic leukemia that uses a patient's own T cells (an approach known as CTL019) may cure some patients and prolong survival in others

Long-Term Remissions of CLL in First Personalized Cell Tx Trial

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T cells reprogrammed to contain chimeric antigen receptor targeting CD19 protein on B cells
Patients with chronic myeloid leukemia who received a glitazone along with imatinib remained disease-free for up to nearly five years in a study published online Sept. 2 in Nature.

Addition of Glitazone to Chemo May Help Treat CML

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Combining glitazones with standard treatment improved survival in small study
Individuals with type 2 diabetes mellitus may be more prone to developing the neuropathology associated with Alzheimer's disease

Type 2 Diabetes Linked to More Alzheimer’s Neuropathology

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Effect may be driven by tau phosphorylation, researchers say
None of 657 patients who took a daily pill to prevent HIV infection contracted the virus over a period of more than two years

Daily PrEP Prevents HIV Infection in High-Risk Individuals

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Study participants were infected with other sexually transmitted diseases
Vietnam veterans exposed to Agent Orange have a more than doubled risk of developing monoclonal gammopathy of undetermined significance

Agent Orange Tied to MGUS in Vietnam Vets

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Exposed veterans have higher rates of monoclonal gammopathy of undetermined significance
Older patients with acute myeloid leukemia are intense users of health care services and rarely use palliative care and hospice services

Older Cancer Patients Heavily Use Health Care Services

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Regardless of chemo intensity, palliative care, hospice rarely used with acute myeloid leukemia
For patients with diabetic nephropathy receiving an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker

Finerenone Linked to Improved UACR in Diabetic Nephropathy

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Addition of finerenone to ACE inhibitor or ARB tied to reduction in urinary albumin-creatinine ratio
For patients with rheumatoid arthritis with prior biologic exposure

Study Compares Hospitalized Infection Risk for Biologics in RA

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Risk of hospitalized infection increased with etanercept, infliximab, rituximab versus abatacept