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Specific loss of heterozygosity is a marker for oral cancer risk

Loss of Heterozygosity Validated As Marker for Oral Cancer

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EGFR inhibitor erlotinib doesn't improve cancer-free survival in high-risk LOH-positive patients
For young women aged 40 to 49 years

Add-On Ultrasonography Ups Mammogram Sensitivity

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Increases sensitivity and detection rate of early breast cancers in women aged 40 to 49 years
Insulin-based strategies of basal rate reduction or pump cessation may be the best approach in avoiding hypoglycemia associated with exercise after lunch

Specific Insulin-Based Exercise Strategies Help in T1DM Pump Tx

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Limit by reducing basal rate by 80 percent or stopping pump for moderate or intense exercise
Use of estimated glomerular filtration rate rather than serum creatinine can expand metformin eligibility

Metformin Eligibility Up With eGFR Versus Serum Creatinine

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Metformin eligibility expanded with use of eGFR, especially among men, non-Hispanic blacks
The correlation between sleep-disordered breathing and glucose metabolism varies for rapid eye movement (REM) sleep and non-REM sleep

Sleep-Disordered Breathing in REM Linked to Insulin Resistance

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Link between sleep-disordered breathing, glucose metabolism varies for REM, non-REM sleep
Two novel collagen structures have been revealed by second harmonic generation imaging of the human corneal limbus. The findings were published in the September issue of Investigative Ophthalmology & Visual Science.

Two Novel Collagen Structures ID’d in Human Corneal Limbus

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Second harmonic generation imaging reveals anterior limbal cribriform layer, presumed anchoring fibers
There is significant cost variation between competing treatments for low-risk prostate cancer

Significant Variation in Tx Costs for Low-Risk Prostate Cancer

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Large cost variation over 12 years of follow-up due to equipment, visits
Another research team is reporting progress toward developing a vaccine to prevent respiratory syncytial virus. Their findings were published in the Nov. 4 issue of Science Translational Medicine.

Progress Made in Early Trial of RSV Vaccine

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Researcher hopes to see routine respiratory syncytial virus immunization within a decade
Raloxifene doesn't benefit cognition in women who have mild to moderate dementia due to Alzheimer's disease

Raloxifene Does Not Appear to Boost Cognition in Alzheimer’s

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Researchers find no cognitive benefits from raloxifene in women with mild to moderate dementia
Cancer cells transmitted from a common tapeworm appear to have caused cancer-like tumors in a Colombian man with HIV -- the first known case of malignant transformation

CDC: Tapeworm Implicated in Case of Malignant Transformation

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Researchers say this is first known case of the parasite causing tumors in a human