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Social jetlag due to a habitual discrepancy between endogenous circadian rhythm and actual sleep times

Social Jetlag Tied to Prediabetes, Cardiovascular Disease Risk

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Misalignment of sleep timing associated with metabolic risk factors, even after adjustment
Light therapy

Bright Light Therapy Might Also Treat Nonseasonal Depression

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Treatment for seasonal affective disorder could have broader application
Animal studies have uncovered a compound that might reduce the adverse effects of levodopa. The research was published in the Nov. 18 issue of Neuron.

New Compound May Help Reduce Side Effects From Levodopa

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Studies in mice, monkeys point to a compound that might lessen levodopa's debilitating effects
Medical management delivered via group medical appointments appears to be effective for glycemic control in patients with type 2 diabetes

Group Medicine Appointments Effective for Glycemic Control

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Greater proportion of patients with T2DM reach target HbA1c levels; faster rate of HbA1c decline
Germline mutations are found in cancer-predisposing genes in 8.5 percent of children and adolescents with cancer

Germline Mutations ID’d in 8.5 Percent of Children With Cancer

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Germline mutations found in cancer-predisposing genes of 8.5 percent of 1,120 children, teens
For patients with prediabetes

Sildenafil Improves Insulin Sensitivity in Prediabetes

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Decrease in plasminogen activator inhibitor-1 without affecting tissue-plasminogen activator
Rosuvastatin appears to be more effective than atorvastatin for regression of coronary atherosclerotic plaques

Meta-Analysis: Rosuvastatin May Be Superior for Plaque Regression

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Rosuvastatin more effective than atorvastatin for reversion of coronary atherosclerotic plaques
Smokeless tobacco users have higher levels of nicotine and carcinogenic tobacco-specific nitrosamines compared with exclusive cigarette smokers

Nicotine, Toxicants Up With Smokeless Tobacco Exposure

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Exclusive smokeless tobacco users have higher levels compared with exclusive cigarette smokers
A new small study is adding evidence to the theory that insulin resistance may play a leading role in some cases of depression. Findings from the study were published online Oct. 12 in Psychiatry Research.

Pioglitazone Found to Help Some With Unremitting Depression

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Insulin resistance may underlie some cases, researchers say
For patients with rheumatoid arthritis

Three-Month Efficacy Data Predicts Six-Month RA Tx Efficacy

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ΔACR50 at six months was strongly correlated with results obtained at three months