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Sleep fragmentation negatively linked to physical and social QoL; N2 stage moderates deleterious effects of fragmentation

Hypoglossal nerve stimulator implantation effective for children with Down syndrome aged younger than 13 years

High continuous metabolic syndrome severity score trajectory pattern linked to increased risk for CKD in adjusted analyses

Dalbavancin not superior to standard therapy, but met the noninferiority criterion

Positive associations seen for celiac disease, SLE, T1D with pancreatic, esophageal, colon, liver, and hepatobiliary cancers

43.2 percent missed opportunity rate reported for germline genetic testing, risk-reducing surgery in those with affected first-degree relative

Cardiovascular diseases contribute less to overall disease burden among centenarians; malignancies account for larger share of disease profile

Independent association seen for complete or partial renal response and lupus low disease activity state with lupus nephritis relapse risk reduction

Children with guideline-confirmed diagnosis have greater improvement in lung function and a higher risk for acute asthma events

Improved maximum urinary flow rate and lower International Prostate Symptom Scores seen for adherent versus nonadherent patients