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Cumulative Epilepsy Risk Higher After Neonatal Seizures

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Highest risk for epilepsy seen for seizure etiologies of neonatal cerebral infarction, hemorrhage, or malformations

Systolic BP Target <120 mm Hg Favored for Most Participants in BP Intervention Trial

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Almost all older adults in SPRINT trial have predicted net benefit favoring systolic BP target <120 mm Hg versus <140 mm Hg

Sisters of Those With Adverse Pregnancy Outcome Also Have Increased CVD Risk

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Women with APO and their APO-free sisters both have increased risks relative to unrelated APO-free comparators

Higher Calcium Intake Linked to Reduced Colorectal Cancer Risk

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Among non-Hispanic Black participants, no association was seen for total calcium intake with CRC risk

Epidural Steroid Injections Reviewed for Radicular Pain, Spinal Stenosis

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Some evidence seen for ESIs reducing pain and disability in cervical and lumbar radiculopathies and possibly in lumbar spinal stenosis

Acalabrutinib-Venetoclax Prolongs Survival in Previously Untreated Leukemia

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Progression-free survival significantly lower with fixed-duration acalabrutinib-venetoclax with or without obinutuzumab

Olpasiran Leads to Significant Reduction in Oxidized Phospholipids

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Olpasiran leads to significant and sustained reduction in OxPL on apolipoprotein B

Certain Glucose-Lowering Meds Associated With Lower Risk for COPD Exacerbations

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Lower risk for COPD exacerbations seen with SGLT-2 inhibitors and GLP-1 receptor agonists, but not with DPP-4 inhibitors

Postpandemic Hospital Occupancy Up to 73.5 Percent, Sparking Concern

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National hospital occupancy of about 85 percent expected by 2032 for adult beds, by 2035 for adult and pediatric beds combined

Black Patients With Cancer Still Have Higher Mortality Rates Than Whites

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Relative decline seen in cancer mortality among Blacks, but they still have higher mortality rates than Whites