Archives
AACR: Nonsurgical Treatment Feasible for Mismatch Repair-Deficient Tumors
Neoadjuvant PD-1 blockade with dostarlimab enables nonoperative management strategy for large proportion of patients
DDW: Systematic Program Increases Likelihood of Up-to-Date Colorectal Cancer Screening
Approximate doubling of up-to-date status seen among Asian, Black, Hispanic, White patients, with corresponding decrease in CRC incidence, deaths
DDW: Certain Proteins Predict Metabolic Dysfunction-Associated Steatotic Liver Disease
Significant deviations seen in plasma concentrations of five proteins up to 16 years before onset of MASLD
CBD Cannabis Extracts Could Reduce Autism Symptoms in Youth
Review shows benefits for social responsiveness, disruptive behavior, and anxiety
Longer Exposure to Antidepressants Increases Risk for Sudden Cardiac Death
Generally, difference in risk associated with antidepressant exposure decreases with age
Breast Surgery Can Be Omitted After Neoadjuvant Systemic Therapy in Select Patients
Patients with initial nodal metastases and breast pCR on vacuum-assisted biopsy who underwent targeted axillary dissection had axillary pCR
AAN: Tolebrutinib Slows Disability in Nonrelapsing Secondary Progressive MS
Tolebrutinib treatment associated with 31 percent risk reduction in six-month confirmed disability progression versus placebo
AAN: Tavapadon as Adjunct to Levodopa Ups Daily ON Time in Parkinson Disease
Significant reduction also seen in change from baseline in daily OFF times versus placebo
ACP: Guidance Provided for Use of Cannabis in Chronic Noncancer Pain Management
Physicians should counsel patients considering whether to start treatment for chronic noncancer pain about benefits and harms of cannabis or cannabinoids
ACP: AI Recommendations More Often Better Quality for Virtual Care Visits
AI recommendations more often rated as optimal compared with treating physician decisions