Archives
Study Quantifies Risk for Gastric, Breast Cancer for Germline CDH1 P/LP Variants
Lifetime cumulative risk for advanced gastric cancer 10.3 and 6.5 percent for male and female carriers, respectively
Reteplase Superior to Alteplase Within 4.5 Hours of Ischemic Stroke
Reteplase more likely to result in excellent functional outcome than alteplase for ischemic stroke within 4.5 hours of symptom onset
Multimodal Intervention Does Not Cut Opioid Overdose Deaths
No significant reduction seen in opioid overdose deaths with implementation of evidence-based practice strategies
Amino Acids Reduced Acute Kidney Injury After Cardiac Surgery
Benefits seen without any increase in adverse events
Multimodal Antiobesity Medications Yield Superior Preoperative Weight Loss
Findings seen in high-risk patients with body mass index ≥70 preparing to undergo metabolic surgery
Lebrikizumab Tied to Sustained Atopic Dermatitis Treatment Effect
Findings seen despite negligible remaining lebrikizumab serum concentrations following treatment withdrawal
Pantoprazole Cuts GI Bleeding in Patients Undergoing Invasive Ventilation
Pantoprazole yields lower clinically important upper GI bleeding, with no significant change in mortality versus placebo
Bariatric Surgery Cuts Conversion to Diabetes Over Long-Term Follow-Up
Findings seen at five, 10, and 15 years following surgery versus nonsurgical, matched controls
Survodutide Tied to Significant Improvement in Fatty Liver Disease
Benefits seen without worsening of fibrosis over 48 weeks
Prolonged β-Lactam Antibiotic Infusions Aid Sepsis, Septic Shock Outcomes
Lower risk seen for 90-day mortality and intensive care unit mortality
