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ASCO: Asciminib Has Superior Efficacy to TKIs for Newly Diagnosed Leukemia

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More patients receiving asciminib than investigator-selected tyrosine kinase inhibitor had major molecular response at 48 weeks

ENDO: Crinecerfont Aids Patients With Congenital Adrenal Hyperplasia

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Crinecerfont results in greater decrease from baseline in mean daily glucocorticoid dose among patients with CAH

ASCO: Stepped-Care Model Noninferior to Early Palliative Care for Advanced Cancer

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Fewer palliative care visits seen with stepped-care model, but noninferiority seen in the Functional Assessment of Cancer Therapy-Lung score

BMI Cutoff of 30 for Obesity May Be Too High for Middle-Aged, Older Adults

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Authors found that BMI of ≥27 shows excellent diagnostic performance

Semaglutide Cuts Risk for Kidney Outcomes, Death in CKD With T2DM

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Reduction seen in risk for clinically important kidney outcomes and death from cardiovascular causes

Pulmonologist Intervention Beneficial for Undiagnosed Asthma, COPD

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Those receiving pulmonologist-directed treatment have less subsequent health care utilization for respiratory illness

Researchers Compare Race-Based, Race-Neutral Lung Function Equations

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Similarly accurate prediction seen for respiratory outcomes, but occupational eligibility and disability compensation differed

Dupilumab Tied to Fewer Exacerbations in COPD With Type 2 Inflammation

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Increase seen in prebronchodilator forced expiratory volume in one second with dupilumab versus placebo at weeks 12, 52

Semaglutide Has Lasting Benefit for Weight Loss

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Second study shows cardiovascular benefit for semaglutide, regardless of weight loss

Survival Benefit for Cancer Trial Participants Does Not Persist in Adjusted Analyses

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Survival benefits disappear when only high-quality studies are pooled and with adjustment for potential publication bias