Archives
Survodutide Tied to Significant Improvement in Fatty Liver Disease
Benefits seen without worsening of fibrosis over 48 weeks
Prolonged β-Lactam Antibiotic Infusions Aid Sepsis, Septic Shock Outcomes
Lower risk seen for 90-day mortality and intensive care unit mortality
Preoxygenation With Noninvasive Ventilation Yields Lower Hypoxemia
Hypoxemia occurred in fewer patients in noninvasive-ventilation group than in oxygen-mask group
Tirzepatide Beneficial for Resolution of MASH in Patients With MASH, Fibrosis
More patients met criteria for resolution of MASH without worsening of fibrosis with 52 weeks of tirzepatide
ENDO: Novel Male Contraceptive Gel May Achieve Faster Sperm Suppression
Gel is combination of segesterone acetate and testosterone
ENDO: Teprotumumab Shows Long-Term Efficacy for Thyroid Eye Disease
Inflammatory and ophthalmic composite outcome improvements seen in 90 percent of patients at 72 weeks
ENDO: Early Menopause Tied to Heightened Risk for Breast, Ovarian Cancer
Primary ovarian insufficiency also tied to higher risk for breast cancer
ASCO: Ivonescimab Improves Progression-Free Survival in EGFR+ Lung Cancer
PFS benefit seen in most subgroups, including those whose disease progressed while receiving third-generation EGFR-TKIs
ASCO: Osimertinib Improves Progression-Free Survival in EGFR-Mutated Lung Cancer
Significantly longer progression-free survival, but not overall survival, seen for osimertinib in unresectable EGFR-mutation NSCLC
ASCO: Neoadjuvant Ipilimumab + Nivolumab Ups Survival in Resectable Melanoma
Neoadjuvant treatment followed by surgery results in longer event-free survival for resectable, macroscopic stage III melanoma