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ADA: Tirzepatide Reduces Apnea-Hypopnea Index in Moderate-to-Severe OSA

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Two randomized controlled trials show reduction in AHI; significant improvements seen in all secondary end points

Echocardiogram Can ID Women With Preeclampsia at Risk for Future HTN

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Authors say findings can inform follow-up care for individuals with preeclampsia

Study Quantifies Risk for Gastric, Breast Cancer for Germline CDH1 P/LP Variants

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Lifetime cumulative risk for advanced gastric cancer 10.3 and 6.5 percent for male and female carriers, respectively

Reteplase Superior to Alteplase Within 4.5 Hours of Ischemic Stroke

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Reteplase more likely to result in excellent functional outcome than alteplase for ischemic stroke within 4.5 hours of symptom onset

Multimodal Intervention Does Not Cut Opioid Overdose Deaths

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No significant reduction seen in opioid overdose deaths with implementation of evidence-based practice strategies

Amino Acids Reduced Acute Kidney Injury After Cardiac Surgery

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Benefits seen without any increase in adverse events

Multimodal Antiobesity Medications Yield Superior Preoperative Weight Loss

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Findings seen in high-risk patients with body mass index ≥70 preparing to undergo metabolic surgery

Lebrikizumab Tied to Sustained Atopic Dermatitis Treatment Effect

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Findings seen despite negligible remaining lebrikizumab serum concentrations following treatment withdrawal

Pantoprazole Cuts GI Bleeding in Patients Undergoing Invasive Ventilation

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Pantoprazole yields lower clinically important upper GI bleeding, with no significant change in mortality versus placebo

Bariatric Surgery Cuts Conversion to Diabetes Over Long-Term Follow-Up

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Findings seen at five, 10, and 15 years following surgery versus nonsurgical, matched controls