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For women with human epidermal growth factor receptor type 2-negative breast cancer receiving anthracycline chemotherapy

ACC: Carvedilol Doesn’t Prevent Anthracycline Cardiotoxicity

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Carvedilol does not prevent reduction in LVEF in breast cancer but is linked to lower troponin I levels
For patients with gout and cardiovascular disease

ACC: Febuxostat Noninferior to Allopurinol for Gout, CVD

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Noninferior for rates of adverse cardiovascular events; tied to higher all-cause, cardiovascular mortality
Men have increased incidence of cervical sprains and fractures associated with sports

AAOS: Football Is Leading Cause of Cervical Injury in U.S.

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Incidence of injuries in males was 1.7 and 3.6 times greater than for females for neck sprains, fractures
Despite low-level evidence

AAOS: Stem Cell Tx for Knee OA Costs About $5,000 Per Injection

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High cost, rapidly expanding use despite low-level evidence; mean marketed clinical efficacy of 82.2%
Participation in sports

AAOS: Participation in Sports Safe After Total Knee Arthroplasty

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Only 3 patients in sports cohort had further operative intervention; no component revisions performed
High fish intake is associated with reduced risk of multiple sclerosis

AAN: High Fish Intake Linked to Reduced Risk of Multiple Sclerosis

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Two tag SNPs in fatty acid desaturase gene 2 independently linked to reduced risk of MS
American-style football athletes have cardiovascular changes indicative of increased cardiovascular risk

ACC: Football Players Show Heart Changes Indicative of CVD Risk

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Aortic root dilation, increased systolic BP, reduced diastolic and vascular function, LV hypertrophy
Large changes in temperature are associated with increased risk of ST-segment elevation myocardial infarction

ACC: Dramatic Changes in Temperature Tied to STEMI Risk

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The effect was exaggerated with larger average daily temperatures
There is a correlation for increased risk of amyotrophic lateral sclerosis with increased occupational exposures to diesel exhaust

AAN: Occupational Exposure to Diesel Exhaust Tied to ALS Risk

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Increased odds of ALS for men in the highest quartile of exposure for five- and 10-year lag periods
Balanced crystalloids offer some benefits versus saline in critically ill and noncritically ill adults

Balanced Crystalloids Cut Kidney Events in Critically Ill

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For noncritically ill patients, no difference in number of hospital-free days for crystalloids versus saline