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Obtaining Second Opinion Delays Treatment for Breast Cancer, but Not Appreciably

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Median time from biopsy to first treatment longer for patients who seek second opinion but still within guidelines

Buprenorphine for Opioid Use Disorder in Pregnancy Can Improve Outcomes

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Buprenorphine linked to reduced rate of adverse outcomes, including severe maternal morbidity, NICU admissions, and preterm births

Withdrawal of Flovent Led to Discontinuation of Inhaled Steroids for Children With Asthma

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Withdrawal of brand-name drug linked to discontinuation of inhaled steroid therapy among children using fluticasone propionate

Metformin Beneficial for Osteoarthritis Knee Pain in Overweight, Obesity

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Mean change in visual analog scale pain greater with metformin versus placebo for patients with symptomatic knee osteoarthritis

AACR: Pretrained Machine Learning Models Help Diagnose Nonmelanoma Skin Cancer

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Leveraging whole slide embeddings from pretrained machine learning models can improve diagnosis of nonmelanoma skin cancer

AACR: Incidence-Based Mortality Dropping for Young Women With Breast Cancer

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Highest incidence-based mortality seen in non-Hispanic Black women, with declines pronounced from 2016, narrowing gap with other racial groups

AACR: Nonsurgical Treatment Feasible for Mismatch Repair-Deficient Tumors

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Neoadjuvant PD-1 blockade with dostarlimab enables nonoperative management strategy for large proportion of patients

DDW: Systematic Program Increases Likelihood of Up-to-Date Colorectal Cancer Screening

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Approximate doubling of up-to-date status seen among Asian, Black, Hispanic, White patients, with corresponding decrease in CRC incidence, deaths

DDW: Certain Proteins Predict Metabolic Dysfunction-Associated Steatotic Liver Disease

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Significant deviations seen in plasma concentrations of five proteins up to 16 years before onset of MASLD

CBD Cannabis Extracts Could Reduce Autism Symptoms in Youth

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Review shows benefits for social responsiveness, disruptive behavior, and anxiety