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Only a small proportion of recommendations in major cardiovascular society guidelines are supported by evidence from multiple randomized controlled trials (RCTs) or a single large RCT

ACC: Robust Evidence Lacking for Many Cardiovascular Guidelines

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Few recommendations in cardiovascular society guidelines supported by evidence from multiple RCTs
For patients with atrial fibrillation

ACC: Catheter Ablation Does Not Cut Mortality, Stroke in A-Fib

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But it is associated with more favorable quality-of-life end points at 12 months versus medical therapy
For statin-treated patients with elevated triglycerides and established cardiovascular disease or diabetes

ACC: Icosapent Ethyl Beneficial for Statin-Treated Patients

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Risk for ischemic events lower for patients with elevated triglycerides and atherosclerosis or diabetes
For patients undergoing elective coronary artery bypass grafting

Volatile Anesthetics Do Not Reduce Deaths in Elective CABG

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No significant difference seen for patients undergoing CABG with volatile anesthesia, total IV anesthesia
For patients with localized prostate cancer

Testosterone Replacement Slows Prostate Cancer Recurrence

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Being on testosterone replacement slows time to biochemical recurrence in multivariable analysis
Few patients are optimally adherent to statins

ACC: Adherence to Statins Low Among Patients With ASCVD

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Adherence linked to significantly reduced risk for MACE, but only 6.4 percent had optimal compliance
Higher consumption of dietary cholesterol

ACC: Dietary Cholesterol Ups Cardiovascular Disease Risk

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Findings show dose-response increase in risk for cardiovascular disease, all-cause mortality
An antibacterial envelope can reduce the incidence of major cardiac implantable electronic device infections

ACC: Antibacterial Envelope Can Reduce CIED Infections

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Incidence of major cardiac implantable electronic device infections significantly lower with envelope
Of patients diagnosed with osteoporosis who have a history of hip fracture

AAOS: Supplement Use Low in Patients With Osteoporosis, Hip Fracture

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Non-Caucasian minorities less likely to receive proper supplementation
Underweight patients have a high number of adverse events and postoperative infections after total shoulder arthroplasty

AAOS: Underweight Status Increases Shoulder Arthroplasty Complications

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Physicians, health care systems should pay more attention to this 'extremely at-risk population'