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Treatment with metformin versus sulfonylureas is associated with a reduced risk for major adverse cardiovascular events among patients with type 2 diabetes and reduced kidney function

CV Risk Lower With Metformin in T2DM + Reduced Kidney Function

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Risk for major adverse cardiovascular events reduced with metformin compared with a sulfonylurea
In adults with recent stroke

Lower Systolic BP Goal May Cut Risk for Orthostatic Hypotension

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Lower systolic BP goal did not affect dizziness or lightheadedness in adults with recent stroke
For adults aged 55 years and older

Greater Cognitive Decline Seen in Seniors Unaware of Having HTN

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Those on antihypertensive treatment have smaller cognition decline, similar to those without HTN
Mortality rate trends for newly diagnosed heart failure patients indicate that the overall reduction in mortality across all age groups is being hindered by high and increasing rates of noncardiovascular events

Decline in Heart Failure Mortality Rates Offset by Comorbidities

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Treatments focused only on cardiovascular outcomes insufficient for improving heart failure patient survival
In updated guidelines developed by the European Society of Cardiology

ESC Guidelines Updated for Managing CVD in Diabetes

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Guidelines address lifestyle recommendations, individualized BP targets, SGLT2 inhibitor, GLP1-RA tx
For patients with type 2 diabetes and obesity

Metabolic Surgery May Reduce CV Risk in T2DM With Obesity

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Reduction seen in primary end point and seven prespecified secondary outcomes, including mortality
Mortality rates and leading causes of death among adults vary across country income levels

Leading Causes of Adult Mortality Vary by Country Income Levels

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Modifiable risk factors account for about 70 percent of cardiovascular disease cases, deaths
For patients with heart failure and reduced ejection fraction

Sacubitril-Valsartan Does Not Impact Aortic Stiffness in HFrEF

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But it is linked to improvements in cardiac structure, function including decreases in LVESVI, LVEDVI
In guidelines developed by the European Society of Cardiology

ESC Guidelines Updated for Diagnosis, Treatment of PE

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Dedicated algorithms proposed for management of high-risk PE, diagnosis of suspected PE in pregnancy
In guidelines developed by the European Society of Cardiology

ESC Guidelines Updated for Supraventricular Tachycardia

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Catheter ablation recommended, should be considered for many patients with SVT