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Nivolumab combined with cabozantinib is superior to sunitinib alone for the treatment of advanced clear cell renal cell carcinoma

Immunotherapy Combo Treats Advanced Kidney Cancer

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First results show survival benefit with nivolumab plus cabozantinib versus sunitinib
A machine learning-based risk calculator may help predict bipolar disorder at age 22 years by using information collected at a visit at age 18 years

Machine Learning Algorithm May Help Predict Bipolar Disorder

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Algorithm applied at a patient visit at age 18 years identifies those at risk for bipolar disorder at age 22
Children who have bronchitis at least once before the age of 7 years are more likely to develop lung problems in later life

Bronchitis in Early Childhood Linked to Later Lung Disease

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Lung diseases occurring later in life more likely to be asthma, pneumonia rather than chronic bronchitis
Electroconvulsive therapy may help treat features of bipolar depression

ECT May Reduce Suicide Risk in Patients With Bipolar Depression

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Authors of cohort study report 84.4 percent decrease in suicidality after electroconvulsive therapy
Pancreas size and shape can be restored with remission of type 2 diabetes

Pancreas Size, Shape Restored With Remission of T2DM

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Responders had increase in pancreas volume, normalization of irregular pancreas borders
Having two or more moderate or severe menopausal symptoms is associated with an increased risk for stroke and cardiovascular disease

Stroke, CVD Risk Up With Two or More Menopausal Symptoms

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No association seen between the severity of vasomotor symptoms and any health outcomes
Rheumatoid arthritis is associated with an increased risk for diabetes mellitus incidence

Rheumatoid Arthritis Linked to Higher Risk for Type 2 Diabetes

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RA linked to increased risk for developing diabetes; association remained in sensitivity analysis
Diagnoses of common conditions decreased substantially between March and May 2020

Diagnoses of Common Conditions Declined in March to May 2020

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Common mental health diagnoses reduced 50 percent; similar drops seen in circulatory system diseases, T2DM
For patients with type 2 diabetes

Once-Weekly Insulin Icodec Promising for Type 2 Diabetes

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In phase 2 study, glucose-lowering efficacy, safety profile similar to once-daily insulin glargine U100
Cancer patients treated one to three months prior to COVID-19 diagnosis and those treated with chemoimmunotherapy have the highest 30-day mortality

Study Examines Effect of Cancer Treatment on COVID-19 Mortality

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Highest 30-day mortality seen with cancer treatment one to three months before COVID-19 diagnosis