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The rate of germline BRCA1/2 and ATM mutations is significantly higher among patients with lethal prostate cancer and is an independent predictor of lethal prostate cancer

BRCA1/2, ATM Mutations ID Risk for Lethal Prostate Cancer

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After adjustment for covariates, mutation carrier remained independent predictor of lethal PCa
Loss of argininosuccinate synthetase 1

ASS1 Loss Identified in Invasive Bladder Cancer

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ASS1-deficient cells were preferentially sensitive to ADI-PEG 20, as shown by reduced cell viability
The estimated prevalence of attrition is 18 percent among general surgery residents

Attrition Prevalence 18 Percent for General Surgery Residents

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Attrition significantly more common for females; uncontrollable lifestyle common cause of attrition
Magnetic resonance imaging (MRI) and MRI-targeted biopsies have a role in the diagnosis and treatment of patients with a prior negative prostate biopsy

MRI Has a Role to Play After Negative Prostate Biopsy

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Magnetic resonance imaging, MRI-targeted biopsy facilitate detection of clinically significant disease
For patients with prostate cancer

Methylation of PITX2 DNA Feasible in Prostate Biopsies

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Can add prognostic information for risk assessment in presurgical diagnostic setting
The prevalence of disability is 2.7 percent among medical students at U.S. allopathic medical schools

Prevalence of Disability 2.7 Percent at U.S. Medical Schools

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Most common disability is ADHD followed by learning disabilities and psychological disabilities
Specific learning interventions may improve emotional well-being among medical students

Learning Interventions Can Improve Med Student Well-Being

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Environmental interventions such as pass/fail grading system, mental health programs beneficial
Cancer cases rose 33 percent worldwide in the past 10 years

Number of Cancer Cases, Deaths Up Globally

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Researchers cite population aging and growth
For older adults

Post-Op Readmission Linked to Delays in Functional Recovery

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Having two or more readmissions within 18 months linked to elevated risk of dependence in IADL, ADL
Erectile dysfunction is tied to higher circulating concentrations of high-sensitivity cardiac troponin I

Erectile Dysfunction Tied to Subclinical Myocardial Injury

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Findings based on association between ED, levels of circulating cardiac troponin I