Increased Flexibility Seen in Preapproval Evidence for New Drugs
Twenty-eight percent of trials used historical, external, or other control; nearly half used surrogate measure as a primary end point
AUA: Outcomes of Robotic, Open Cystectomy Compared in Bladder Cancer
Number of days alive and out of hospital within first 90 days greater for robot-assisted surgery, but clinical significance of findings unclear
mRNA-1273 Induces Stronger Response Than BNT162b2 for Immunosuppressed
Findings seen in immunosuppressed patients with rheumatic and musculoskeletal diseases, solid organ transplant recipients
AUA: Pandemic Disruptions Impacted One in Four Prostate, Bladder Cancer Patients
Changes, delays, and cancellation of cancer treatment and ancillary care reported
AUA: Kidney Transplants From COVID-19-Infected Donors Are Safe
Recipient outcomes similar to kidneys from noninfected donors
DDW: Gallstone Disease May Predict Pancreatic Cancer Incidence
Gallstone presentation may be a missed opportunity for earlier diagnosis
TXA Seems Safe for Surgery in High-Risk Patients With IT Hip Fracture
No increased risk for mortality or thromboembolic complications seen with use of tranexamic acid among high-risk patients, entire cohort
Subcutaneous Implantable Defibrillators Cut Lead-Related Complications
Risk for major lead-related complications much lower with subcutaneous ICD versus transvenous ICD
Mailed At-Home Disposal Kits Up Opioid Disposal Rates
Mailed kits are a potential low-cost, scalable solution, the authors say
New-Onset Depression Common During Surgical Internship Year
Among surgical interns with no depression at baseline, 32 percent had high enough scores on mood surveys to be considered depressed