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Increased Flexibility Seen in Preapproval Evidence for New Drugs

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Twenty-eight percent of trials used historical, external, or other control; nearly half used surrogate measure as a primary end point

One in Six Older Patients Have Reoperation for Hernia Recurrence

AUA: Outcomes of Robotic, Open Cystectomy Compared in Bladder Cancer

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Number of days alive and out of hospital within first 90 days greater for robot-assisted surgery, but clinical significance of findings unclear

A young woman in a mask decided to get vaccinated against the coronavirus during the pandemic by an experienced doctor in the laboratory.

mRNA-1273 Induces Stronger Response Than BNT162b2 for Immunosuppressed

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Findings seen in immunosuppressed patients with rheumatic and musculoskeletal diseases, solid organ transplant recipients

Female nurse measuring blood pressure to adult senior man in the hospital

AUA: Pandemic Disruptions Impacted One in Four Prostate, Bladder Cancer Patients

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Changes, delays, and cancellation of cancer treatment and ancillary care reported

Long-Term QOL Examined for Surgical Choices in Breast Cancer

AUA: Kidney Transplants From COVID-19-Infected Donors Are Safe

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Recipient outcomes similar to kidneys from noninfected donors

HTN Meds Tied to Lower Mortality After Pancreatic Cancer Diagnosis

DDW: Gallstone Disease May Predict Pancreatic Cancer Incidence

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Gallstone presentation may be a missed opportunity for earlier diagnosis

Intra-Articular Injection of Triamcinolone Beneficial in Hip Osteoarthritis

TXA Seems Safe for Surgery in High-Risk Patients With IT Hip Fracture

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No increased risk for mortality or thromboembolic complications seen with use of tranexamic acid among high-risk patients, entire cohort

Early Rhythm Control Key in A-Fib and Heart Failure

Subcutaneous Implantable Defibrillators Cut Lead-Related Complications

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Risk for major lead-related complications much lower with subcutaneous ICD versus transvenous ICD

Adolescents and Opioids

Mailed At-Home Disposal Kits Up Opioid Disposal Rates

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Mailed kits are a potential low-cost, scalable solution, the authors say

New-Onset Depression Common During Surgical Internship Year

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Among surgical interns with no depression at baseline, 32 percent had high enough scores on mood surveys to be considered depressed