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Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction

Dupilumab Cuts Exacerbations in Late-Onset Asthma

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Lung function improved at weeks 12 and 52 in patients with, without fixed airway obstruction
Four distinct clinical phenotypes have been identified among patients with sepsis

Four Clinical Phenotypes Identified for Sepsis

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Phenotype distributions similar in derivation, validation cohorts; highest mortality for γ phenotype
A bill to raise the minimum age for buying any type of tobacco product

Bill Would Raise U.S. Legal Age to Buy Tobacco to 21

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Fourteen states have already enacted laws raising the minimum age for tobacco sales to 21
For patients with moderate-to-severe acute respiratory distress syndrome receiving mechanical ventilation

Early Neuromuscular Blockade No Better in ARDS Patients on Vent

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Mortality similar for those receiving continuous infusion of cisatracurium, lighter sedation targets
For patients with mild asthma with a low sputum eosinophil level

Mometasone, Tiotropium Do Not Top Placebo in Mild Asthma

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And budesonide-formoterol superior to albuterol for prevention of asthma exacerbations
Prices paid to hospitals for privately insured patients in 2017 averaged 241 percent of what Medicare would have paid

Private Insurers Pay 241 Percent of What Medicare Would Pay

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RAND researchers recommend private insurers move toward fixed-price arrangements
More than 50

Many Lives Could Be Saved if All Hospitals Had Grade A Rating

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Patients at D, F hospitals have 91.8 percent increased risk for avoidable death compared with A hospitals
For patients with locally advanced non-small cell lung cancer

AI Model Uses Serial Imaging to Predict Lung Cancer Tx Response

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Deep learning integrates CT scans from multiple time points to improve clinical outcome predictions
Guidelines have been updated for screening and treatment for tuberculosis infection among health care personnel

Recs Updated for TB Screening, Treatment in Health Care Workers

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Guidelines include preplacement TB risk assessment, postexposure symptom evaluation and testing
North Carolina is suing electronic cigarette manufacturer JUUL for allegedly marketing its products to children and misleading the public about the health risks of the products. This lawsuit is the first filed by a state over JUUL's alleged marketing toward teens

North Carolina Sues Electronic Cigarette Maker JUUL

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Also, judge has ruled that the FDA neglected its legal duty by postponing reviews of vaping products