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The use of idalopirdine does not improve cognition versus placebo over 24 weeks of treatment for patients with mild-to-moderate Alzheimer's disease

Idalopirdine May Not Improve Cognition in Mild Alzheimer’s

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Findings from three randomized trials show no improvement in cognition vs. placebo over 24 weeks
The risk of autism spectrum disorder is reduced in offspring with maternal exposure to folic acid and multivitamin supplementation before and during pregnancy

Maternal Folic Acid, Multivitamin Use May Cut ASD Risk in Offspring

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Autism spectrum disorder risk lower in those whose moms took supplements before, while pregnant
For high school students

2005 to 2015 Saw Fewer High School Students Having Sex

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Significant drop in proportion of high school students who had ever had sexual intercourse nationwide
Transcranial direct current stimulation appears to be effective and safe as an add-on intervention for adults with bipolar depression

Transcranial Direct Current Stimulation Promising for Bipolar

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tDCS seems effective and safe for adults with bipolar depression receiving stable pharmacologic regimen
Hospitals that volunteered to be under financial incentives for more than a decade as part of the Premier Hospital Quality Incentive Demonstration do not have better process scores or lower mortality than hospitals where these incentives were implemented later under the Hospital Value-Based Purchasing program

For Hospitals, No Benefit for Early Adoption of Financial Incentives

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Hospitals with early adoption do not have better process scores, lower mortality than late adopters
For patients with type 1 diabetes

Bidirectional Association for Depression, Dysglycemia in T1DM

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Depression increases risk of dysglycemia especially in first six months to one year of diagnosis
Esketamine seems to be efficacious and safe for patients with treatment-resistant depression

Esketamine Safe, Effective for Treatment-Resistant Depression

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Change in Montgomery-Åsberg Depression Rating Scale score superior for esketamine versus placebo
Non-cigarette tobacco use is associated with subsequent cigarette smoking among U.S. adolescents

Non-Cigarette Tobacco Use Tied to Future Cigarette Use in Teens

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E-cigarettes, hookah, non-cigarette combustible tobacco linked with cigarette smoking 1 year later

December 2017 Briefing – Psychiatry

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Here are what the editors at HealthDay consider to be the most important developments in Psychiatry for December 2017. This roundup includes the latest...
For children exposed to antiepileptic drugs in utero

Folic Acid Lessens Autism Risk for Fetal Anti-Epileptic Exposure

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For children exposed to antiepileptic drugs in utero, risk may be mitigated by folic acid supplementation