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For adults with major depressive disorder

21 Reviewed Antidepressants Top Placebo for Major Depression

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Agomelatine, amitriptyline, escitalopram are among most effective agents in head-to-head trials
Chronicity of depression is associated with increased likelihood of failure along the continuum of HIV care

Chronicity of Depression Ups Failure Along Continuum of HIV Care

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25 percent increase in percentage of days with depression ups risk of missing appointment, death
The percentage of uninsured U.S. persons of all ages did not change significantly from 2016 to the first nine months of 2017

CDC: No Change in Percentage of Uninsured in U.S. From ’16 to ’17

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Increase in percentage of those aged younger than 65 years enrolled in high-deductible health plan
A number of kratom-containing dietary supplements are being recalled and destroyed by the manufacturer

FDA Cracks Down on Kratom Products

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Missouri-based Divinity Products Distribution will recall and destroy kratom-containing products
Introduction of a new model of screening and protocoled treatment with medications for opioid addiction treatment

Treatment Model Linked to Drop in Post-Incarceration Overdoses

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Introduction of model to treat opioid use disorder tied to drop in overdose deaths after incarceration
Compared with men

Mental Stress-Induced Myocardial Ischemia Risk Up for Women

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Peripheral vasoconstriction, microvascular dysfunction may affect MSIMI risk in women only
Many patients with non-cancer-related chronic pain prescribed long-term opioids may wish to taper their opioid use

Chronic Opioid Users May Wish to Taper Opioid Use

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In study completers, median morphine equivalent daily dose fell from 288 mg to 150 mg in four months
Children involved in sibling bullying are at increased risk of developing a psychotic disorder

Sibling Bullying Tied to Increased Odds of Psychotic Disorder

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Both victims and perpetrators have greater odds of developing a psychotic disorder
Burnout is prevalent among physicians

Burnout Found Prevalent Among Doctors in Single Health System

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Link between patient satisfaction and emotional exhaustion; also tied to odds of leaving organization
A toll-like receptor 9 agonist in the presence of alum is stable over a month and elicits strong anti-heroin antibody titers and blockade of heroin-induced antinociception

Anti-Heroin Vaccine Shows Promise Against Lethal Doses

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TLR9 agonist in presence of alum is stable over 30 days, elicits strong anti-heroin antibody titers